Recombinant multi-species hnRNP-E1/PCBP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine hnRNP-E1/PCBP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Alpha-CP1,HEL-S-85,HNRPE1,HNRPX,Heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1),Nucleic acid-binding protein SUB2.3,PCBP1,Pcbp1,Poly(rC)-binding protein 1,RGD1561319,WBP17,[a]CP-1,alphaCP-1,hnRNP E1,hnRNP-E1,hnRNP-X

Target products collectionGo to hnRNP-E1/PCBP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9229-Ag-1/ GM-Tg-hg-IP9229-Ag-2 Human hnRNP-E1/PCBP1 protein Human
GM-Tg-rg-IP9229-Ag-1/ GM-Tg-rg-IP9229-Ag-2 Rat hnRNP-E1/PCBP1 protein Rat
GM-Tg-mg-IP9229-Ag-1/ GM-Tg-mg-IP9229-Ag-2 Mouse hnRNP-E1/PCBP1 protein Mouse
GM-Tg-cynog-IP9229-Ag-1/ GM-Tg-cynog-IP9229-Ag-2 Cynomolgus/Rhesus macaque hnRNP-E1/PCBP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9229-Ag-1/ GM-Tg-felg-IP9229-Ag-2 Feline hnRNP-E1/PCBP1 protein Feline
GM-Tg-cang-IP9229-Ag-1/ GM-Tg-cang-IP9229-Ag-2 Canine hnRNP-E1/PCBP1 protein Canine
GM-Tg-bovg-IP9229-Ag-1/ GM-Tg-bovg-IP9229-Ag-2 Bovine hnRNP-E1/PCBP1 protein Bovine
GM-Tg-equg-IP9229-Ag-1/ GM-Tg-equg-IP9229-Ag-2 Equine hnRNP-E1/PCBP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9229-Ag-1/ GM-Tg-hg-IP9229-Ag-2; GM-Tg-rg-IP9229-Ag-1/ GM-Tg-rg-IP9229-Ag-2;
GM-Tg-mg-IP9229-Ag-1/ GM-Tg-mg-IP9229-Ag-2; GM-Tg-cynog-IP9229-Ag-1/ GM-Tg-cynog-IP9229-Ag-2;
GM-Tg-felg-IP9229-Ag-1/ GM-Tg-felg-IP9229-Ag-2; GM-Tg-cang-IP9229-Ag-1/ GM-Tg-cang-IP9229-Ag-2;
GM-Tg-bovg-IP9229-Ag-1/ GM-Tg-bovg-IP9229-Ag-2; GM-Tg-equg-IP9229-Ag-1/ GM-Tg-equg-IP9229-Ag-2
Products Name hnRNP-E1/PCBP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name hnRNP-E1/PCBP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine hnRNP-E1/PCBP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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