Recombinant multi-species PBX1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PBX1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
The Alternative Names of target: 2310056B04Rik,CAKUHED,D230003C07Rik,Homeobox protein PBX1,Homeobox protein PRL,PBX1,Pbx-1,Pbx1,Pre-B-cell leukemia transcription factor 1

Target products collectionGo to PBX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9223-Ag-1/ GM-Tg-hg-IP9223-Ag-2 Human PBX1 protein Human
GM-Tg-rg-IP9223-Ag-1/ GM-Tg-rg-IP9223-Ag-2 Rat PBX1 protein Rat
GM-Tg-mg-IP9223-Ag-1/ GM-Tg-mg-IP9223-Ag-2 Mouse PBX1 protein Mouse
GM-Tg-cynog-IP9223-Ag-1/ GM-Tg-cynog-IP9223-Ag-2 Cynomolgus/Rhesus macaque PBX1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9223-Ag-1/ GM-Tg-felg-IP9223-Ag-2 Feline PBX1 protein Feline
GM-Tg-cang-IP9223-Ag-1/ GM-Tg-cang-IP9223-Ag-2 Canine PBX1 protein Canine
GM-Tg-bovg-IP9223-Ag-1/ GM-Tg-bovg-IP9223-Ag-2 Bovine PBX1 protein Bovine
GM-Tg-equg-IP9223-Ag-1/ GM-Tg-equg-IP9223-Ag-2 Equine PBX1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9223-Ag-1/ GM-Tg-hg-IP9223-Ag-2; GM-Tg-rg-IP9223-Ag-1/ GM-Tg-rg-IP9223-Ag-2;
GM-Tg-mg-IP9223-Ag-1/ GM-Tg-mg-IP9223-Ag-2; GM-Tg-cynog-IP9223-Ag-1/ GM-Tg-cynog-IP9223-Ag-2;
GM-Tg-felg-IP9223-Ag-1/ GM-Tg-felg-IP9223-Ag-2; GM-Tg-cang-IP9223-Ag-1/ GM-Tg-cang-IP9223-Ag-2;
GM-Tg-bovg-IP9223-Ag-1/ GM-Tg-bovg-IP9223-Ag-2; GM-Tg-equg-IP9223-Ag-1/ GM-Tg-equg-IP9223-Ag-2
Products Name PBX1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PBX1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PBX1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.