Recombinant multi-species PARN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PARN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
The Alternative Names of target: 1200003I18Rik,DAN,DKCB6,Deadenylating nuclease,Deadenylation nuclease,PARN,PFBMFT4,Parn,Poly(A)-specific ribonuclease PARN,Polyadenylate-specific ribonuclease,RGD1565449

Target products collectionGo to PARN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9205-Ag-1/ GM-Tg-hg-IP9205-Ag-2 Human PARN protein Human
GM-Tg-rg-IP9205-Ag-1/ GM-Tg-rg-IP9205-Ag-2 Rat PARN protein Rat
GM-Tg-mg-IP9205-Ag-1/ GM-Tg-mg-IP9205-Ag-2 Mouse PARN protein Mouse
GM-Tg-cynog-IP9205-Ag-1/ GM-Tg-cynog-IP9205-Ag-2 Cynomolgus/Rhesus macaque PARN protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9205-Ag-1/ GM-Tg-felg-IP9205-Ag-2 Feline PARN protein Feline
GM-Tg-cang-IP9205-Ag-1/ GM-Tg-cang-IP9205-Ag-2 Canine PARN protein Canine
GM-Tg-bovg-IP9205-Ag-1/ GM-Tg-bovg-IP9205-Ag-2 Bovine PARN protein Bovine
GM-Tg-equg-IP9205-Ag-1/ GM-Tg-equg-IP9205-Ag-2 Equine PARN protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9205-Ag-1/ GM-Tg-hg-IP9205-Ag-2; GM-Tg-rg-IP9205-Ag-1/ GM-Tg-rg-IP9205-Ag-2;
GM-Tg-mg-IP9205-Ag-1/ GM-Tg-mg-IP9205-Ag-2; GM-Tg-cynog-IP9205-Ag-1/ GM-Tg-cynog-IP9205-Ag-2;
GM-Tg-felg-IP9205-Ag-1/ GM-Tg-felg-IP9205-Ag-2; GM-Tg-cang-IP9205-Ag-1/ GM-Tg-cang-IP9205-Ag-2;
GM-Tg-bovg-IP9205-Ag-1/ GM-Tg-bovg-IP9205-Ag-2; GM-Tg-equg-IP9205-Ag-1/ GM-Tg-equg-IP9205-Ag-2
Products Name PARN protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PARN
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PARN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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