Recombinant multi-species ATP5A1/ATP5F1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP5A1/ATP5F1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012]
The Alternative Names of target: ATP synthase F1 subunit alpha,ATP synthase subunit alpha,ATP5A,ATP5A1,ATP5AL2,ATP5F1A,ATPM,Atp5a1,Atp5f1a,Atpm,COXPD22,D18Ertd206e,HEL-S-123m,MC5DN4,MC5DN4A,MC5DN4B,MOM2,Mom2,OMR,ORM,hATP1,mitochondrial
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9164-Ag-1/ GM-Tg-hg-IP9164-Ag-2 | Human ATP5A1/ATP5F1A protein | Human |
| GM-Tg-rg-IP9164-Ag-1/ GM-Tg-rg-IP9164-Ag-2 | Rat ATP5A1/ATP5F1A protein | Rat |
| GM-Tg-mg-IP9164-Ag-1/ GM-Tg-mg-IP9164-Ag-2 | Mouse ATP5A1/ATP5F1A protein | Mouse |
| GM-Tg-cynog-IP9164-Ag-1/ GM-Tg-cynog-IP9164-Ag-2 | Cynomolgus/Rhesus macaque ATP5A1/ATP5F1A protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9164-Ag-1/ GM-Tg-felg-IP9164-Ag-2 | Feline ATP5A1/ATP5F1A protein | Feline |
| GM-Tg-cang-IP9164-Ag-1/ GM-Tg-cang-IP9164-Ag-2 | Canine ATP5A1/ATP5F1A protein | Canine |
| GM-Tg-bovg-IP9164-Ag-1/ GM-Tg-bovg-IP9164-Ag-2 | Bovine ATP5A1/ATP5F1A protein | Bovine |
| GM-Tg-equg-IP9164-Ag-1/ GM-Tg-equg-IP9164-Ag-2 | Equine ATP5A1/ATP5F1A protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9164-Ag-1/ GM-Tg-hg-IP9164-Ag-2;
GM-Tg-rg-IP9164-Ag-1/ GM-Tg-rg-IP9164-Ag-2;
GM-Tg-mg-IP9164-Ag-1/ GM-Tg-mg-IP9164-Ag-2; GM-Tg-cynog-IP9164-Ag-1/ GM-Tg-cynog-IP9164-Ag-2; GM-Tg-felg-IP9164-Ag-1/ GM-Tg-felg-IP9164-Ag-2; GM-Tg-cang-IP9164-Ag-1/ GM-Tg-cang-IP9164-Ag-2; GM-Tg-bovg-IP9164-Ag-1/ GM-Tg-bovg-IP9164-Ag-2; GM-Tg-equg-IP9164-Ag-1/ GM-Tg-equg-IP9164-Ag-2 |
| Products Name | ATP5A1/ATP5F1A protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ATP5A1/ATP5F1A |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP5A1/ATP5F1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
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platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.