Recombinant multi-species ATP5A1/ATP5F1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP5A1/ATP5F1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012]
The Alternative Names of target: ATP synthase F1 subunit alpha,ATP synthase subunit alpha,ATP5A,ATP5A1,ATP5AL2,ATP5F1A,ATPM,Atp5a1,Atp5f1a,Atpm,COXPD22,D18Ertd206e,HEL-S-123m,MC5DN4,MC5DN4A,MC5DN4B,MOM2,Mom2,OMR,ORM,hATP1,mitochondrial

Target products collectionGo to ATP5A1/ATP5F1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9164-Ag-1/ GM-Tg-hg-IP9164-Ag-2 Human ATP5A1/ATP5F1A protein Human
GM-Tg-rg-IP9164-Ag-1/ GM-Tg-rg-IP9164-Ag-2 Rat ATP5A1/ATP5F1A protein Rat
GM-Tg-mg-IP9164-Ag-1/ GM-Tg-mg-IP9164-Ag-2 Mouse ATP5A1/ATP5F1A protein Mouse
GM-Tg-cynog-IP9164-Ag-1/ GM-Tg-cynog-IP9164-Ag-2 Cynomolgus/Rhesus macaque ATP5A1/ATP5F1A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9164-Ag-1/ GM-Tg-felg-IP9164-Ag-2 Feline ATP5A1/ATP5F1A protein Feline
GM-Tg-cang-IP9164-Ag-1/ GM-Tg-cang-IP9164-Ag-2 Canine ATP5A1/ATP5F1A protein Canine
GM-Tg-bovg-IP9164-Ag-1/ GM-Tg-bovg-IP9164-Ag-2 Bovine ATP5A1/ATP5F1A protein Bovine
GM-Tg-equg-IP9164-Ag-1/ GM-Tg-equg-IP9164-Ag-2 Equine ATP5A1/ATP5F1A protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9164-Ag-1/ GM-Tg-hg-IP9164-Ag-2; GM-Tg-rg-IP9164-Ag-1/ GM-Tg-rg-IP9164-Ag-2;
GM-Tg-mg-IP9164-Ag-1/ GM-Tg-mg-IP9164-Ag-2; GM-Tg-cynog-IP9164-Ag-1/ GM-Tg-cynog-IP9164-Ag-2;
GM-Tg-felg-IP9164-Ag-1/ GM-Tg-felg-IP9164-Ag-2; GM-Tg-cang-IP9164-Ag-1/ GM-Tg-cang-IP9164-Ag-2;
GM-Tg-bovg-IP9164-Ag-1/ GM-Tg-bovg-IP9164-Ag-2; GM-Tg-equg-IP9164-Ag-1/ GM-Tg-equg-IP9164-Ag-2
Products Name ATP5A1/ATP5F1A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ATP5A1/ATP5F1A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP5A1/ATP5F1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.