Recombinant multi-species NDUFV1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDUFV1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
The Alternative Names of target: CI-51K,CI-51kD,CI51KD,Complex I-51kD (CI-51kD),MC1DN4,NADH dehydrogenase [ubiquinone] flavoprotein 1,NADH dehydrogenase flavoprotein 1,NADH-ubiquinone oxidoreductase 51 kDa subunit,NDUFV1,Ndufv1,UQOR1,mitochondrial

Target products collectionGo to NDUFV1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9063-Ag-1/ GM-Tg-hg-IP9063-Ag-2 Human NDUFV1 protein Human
GM-Tg-rg-IP9063-Ag-1/ GM-Tg-rg-IP9063-Ag-2 Rat NDUFV1 protein Rat
GM-Tg-mg-IP9063-Ag-1/ GM-Tg-mg-IP9063-Ag-2 Mouse NDUFV1 protein Mouse
GM-Tg-cynog-IP9063-Ag-1/ GM-Tg-cynog-IP9063-Ag-2 Cynomolgus/Rhesus macaque NDUFV1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9063-Ag-1/ GM-Tg-felg-IP9063-Ag-2 Feline NDUFV1 protein Feline
GM-Tg-cang-IP9063-Ag-1/ GM-Tg-cang-IP9063-Ag-2 Canine NDUFV1 protein Canine
GM-Tg-bovg-IP9063-Ag-1/ GM-Tg-bovg-IP9063-Ag-2 Bovine NDUFV1 protein Bovine
GM-Tg-equg-IP9063-Ag-1/ GM-Tg-equg-IP9063-Ag-2 Equine NDUFV1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9063-Ag-1/ GM-Tg-hg-IP9063-Ag-2; GM-Tg-rg-IP9063-Ag-1/ GM-Tg-rg-IP9063-Ag-2;
GM-Tg-mg-IP9063-Ag-1/ GM-Tg-mg-IP9063-Ag-2; GM-Tg-cynog-IP9063-Ag-1/ GM-Tg-cynog-IP9063-Ag-2;
GM-Tg-felg-IP9063-Ag-1/ GM-Tg-felg-IP9063-Ag-2; GM-Tg-cang-IP9063-Ag-1/ GM-Tg-cang-IP9063-Ag-2;
GM-Tg-bovg-IP9063-Ag-1/ GM-Tg-bovg-IP9063-Ag-2; GM-Tg-equg-IP9063-Ag-1/ GM-Tg-equg-IP9063-Ag-2
Products Name NDUFV1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NDUFV1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDUFV1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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