Recombinant multi-species NDUFS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDUFS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
The Alternative Names of target: 5830412M15Rik,9930026A05Rik,CI-75Kd,CI-75k,Complex I-75kD (CI-75kD),MC1DN5,NADH-ubiquinone oxidoreductase 75 kDa subunit,NDUFS1,Ndufs1,PRO1304,mitochondrial

Target products collectionGo to NDUFS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP9060-Ag-1/ GM-Tg-hg-IP9060-Ag-2 Human NDUFS1 protein Human
GM-Tg-rg-IP9060-Ag-1/ GM-Tg-rg-IP9060-Ag-2 Rat NDUFS1 protein Rat
GM-Tg-mg-IP9060-Ag-1/ GM-Tg-mg-IP9060-Ag-2 Mouse NDUFS1 protein Mouse
GM-Tg-cynog-IP9060-Ag-1/ GM-Tg-cynog-IP9060-Ag-2 Cynomolgus/Rhesus macaque NDUFS1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP9060-Ag-1/ GM-Tg-felg-IP9060-Ag-2 Feline NDUFS1 protein Feline
GM-Tg-cang-IP9060-Ag-1/ GM-Tg-cang-IP9060-Ag-2 Canine NDUFS1 protein Canine
GM-Tg-bovg-IP9060-Ag-1/ GM-Tg-bovg-IP9060-Ag-2 Bovine NDUFS1 protein Bovine
GM-Tg-equg-IP9060-Ag-1/ GM-Tg-equg-IP9060-Ag-2 Equine NDUFS1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP9060-Ag-1/ GM-Tg-hg-IP9060-Ag-2; GM-Tg-rg-IP9060-Ag-1/ GM-Tg-rg-IP9060-Ag-2;
GM-Tg-mg-IP9060-Ag-1/ GM-Tg-mg-IP9060-Ag-2; GM-Tg-cynog-IP9060-Ag-1/ GM-Tg-cynog-IP9060-Ag-2;
GM-Tg-felg-IP9060-Ag-1/ GM-Tg-felg-IP9060-Ag-2; GM-Tg-cang-IP9060-Ag-1/ GM-Tg-cang-IP9060-Ag-2;
GM-Tg-bovg-IP9060-Ag-1/ GM-Tg-bovg-IP9060-Ag-2; GM-Tg-equg-IP9060-Ag-1/ GM-Tg-equg-IP9060-Ag-2
Products Name NDUFS1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NDUFS1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDUFS1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.