Recombinant multi-species NDUFS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDUFS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
The Alternative Names of target: 5830412M15Rik,9930026A05Rik,CI-75Kd,CI-75k,Complex I-75kD (CI-75kD),MC1DN5,NADH-ubiquinone oxidoreductase 75 kDa subunit,NDUFS1,Ndufs1,PRO1304,mitochondrial
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9060-Ag-1/ GM-Tg-hg-IP9060-Ag-2 | Human NDUFS1 protein | Human |
| GM-Tg-rg-IP9060-Ag-1/ GM-Tg-rg-IP9060-Ag-2 | Rat NDUFS1 protein | Rat |
| GM-Tg-mg-IP9060-Ag-1/ GM-Tg-mg-IP9060-Ag-2 | Mouse NDUFS1 protein | Mouse |
| GM-Tg-cynog-IP9060-Ag-1/ GM-Tg-cynog-IP9060-Ag-2 | Cynomolgus/Rhesus macaque NDUFS1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9060-Ag-1/ GM-Tg-felg-IP9060-Ag-2 | Feline NDUFS1 protein | Feline |
| GM-Tg-cang-IP9060-Ag-1/ GM-Tg-cang-IP9060-Ag-2 | Canine NDUFS1 protein | Canine |
| GM-Tg-bovg-IP9060-Ag-1/ GM-Tg-bovg-IP9060-Ag-2 | Bovine NDUFS1 protein | Bovine |
| GM-Tg-equg-IP9060-Ag-1/ GM-Tg-equg-IP9060-Ag-2 | Equine NDUFS1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9060-Ag-1/ GM-Tg-hg-IP9060-Ag-2;
GM-Tg-rg-IP9060-Ag-1/ GM-Tg-rg-IP9060-Ag-2;
GM-Tg-mg-IP9060-Ag-1/ GM-Tg-mg-IP9060-Ag-2; GM-Tg-cynog-IP9060-Ag-1/ GM-Tg-cynog-IP9060-Ag-2; GM-Tg-felg-IP9060-Ag-1/ GM-Tg-felg-IP9060-Ag-2; GM-Tg-cang-IP9060-Ag-1/ GM-Tg-cang-IP9060-Ag-2; GM-Tg-bovg-IP9060-Ag-1/ GM-Tg-bovg-IP9060-Ag-2; GM-Tg-equg-IP9060-Ag-1/ GM-Tg-equg-IP9060-Ag-2 |
| Products Name | NDUFS1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | NDUFS1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDUFS1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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GMab, developed by GeneMedi, constitutes an
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myriad domains of biological drug
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.