Recombinant multi-species NOXA2/p67phox/NCF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NOXA2/p67phox/NCF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
The Alternative Names of target: 67 kDa neutrophil oxidase factor,NADPH oxidase activator 2,NCF-2,NCF2,NOXA2,Ncf-2,Ncf2,Neutrophil NADPH oxidase factor 2,Neutrophil cytosol factor 2,P67-PHOX,P67PHOX,p67-phox,p67phox
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP9045-Ag-1/ GM-Tg-hg-IP9045-Ag-2 | Human NOXA2/p67phox/NCF2 protein | Human |
| GM-Tg-rg-IP9045-Ag-1/ GM-Tg-rg-IP9045-Ag-2 | Rat NOXA2/p67phox/NCF2 protein | Rat |
| GM-Tg-mg-IP9045-Ag-1/ GM-Tg-mg-IP9045-Ag-2 | Mouse NOXA2/p67phox/NCF2 protein | Mouse |
| GM-Tg-cynog-IP9045-Ag-1/ GM-Tg-cynog-IP9045-Ag-2 | Cynomolgus/Rhesus macaque NOXA2/p67phox/NCF2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP9045-Ag-1/ GM-Tg-felg-IP9045-Ag-2 | Feline NOXA2/p67phox/NCF2 protein | Feline |
| GM-Tg-cang-IP9045-Ag-1/ GM-Tg-cang-IP9045-Ag-2 | Canine NOXA2/p67phox/NCF2 protein | Canine |
| GM-Tg-bovg-IP9045-Ag-1/ GM-Tg-bovg-IP9045-Ag-2 | Bovine NOXA2/p67phox/NCF2 protein | Bovine |
| GM-Tg-equg-IP9045-Ag-1/ GM-Tg-equg-IP9045-Ag-2 | Equine NOXA2/p67phox/NCF2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP9045-Ag-1/ GM-Tg-hg-IP9045-Ag-2;
GM-Tg-rg-IP9045-Ag-1/ GM-Tg-rg-IP9045-Ag-2;
GM-Tg-mg-IP9045-Ag-1/ GM-Tg-mg-IP9045-Ag-2; GM-Tg-cynog-IP9045-Ag-1/ GM-Tg-cynog-IP9045-Ag-2; GM-Tg-felg-IP9045-Ag-1/ GM-Tg-felg-IP9045-Ag-2; GM-Tg-cang-IP9045-Ag-1/ GM-Tg-cang-IP9045-Ag-2; GM-Tg-bovg-IP9045-Ag-1/ GM-Tg-bovg-IP9045-Ag-2; GM-Tg-equg-IP9045-Ag-1/ GM-Tg-equg-IP9045-Ag-2 |
| Products Name | NOXA2/p67phox/NCF2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | NOXA2/p67phox/NCF2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NOXA2/p67phox/NCF2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.