Recombinant multi-species MLLT3/AF9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MLLT3/AF9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Enables chromatin binding activity; lysine-acetylated histone binding activity; and molecular adaptor activity. Involved in several processes, including hematopoietic stem cell differentiation; positive regulation of DNA-templated transcription; and regulation of stem cell division. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and positive regulation of Wnt signaling pathway, planar cell polarity pathway. Located in cytosol and nucleoplasm. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Feb 2025]
The Alternative Names of target: 2210011H10Rik,2610012I03Rik,3830408D16Rik,AF9,ALL1-fused gene from chromosome 9 protein,Af-9,Af9,D4Ertd321e,MLLT3,Mllt3,Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein,Protein AF-9,YEATS domain-containing protein 3,YEATS3
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP8842-Ag-1/ GM-Tg-hg-IP8842-Ag-2 | Human MLLT3/AF9 protein | Human |
| GM-Tg-rg-IP8842-Ag-1/ GM-Tg-rg-IP8842-Ag-2 | Rat MLLT3/AF9 protein | Rat |
| GM-Tg-mg-IP8842-Ag-1/ GM-Tg-mg-IP8842-Ag-2 | Mouse MLLT3/AF9 protein | Mouse |
| GM-Tg-cynog-IP8842-Ag-1/ GM-Tg-cynog-IP8842-Ag-2 | Cynomolgus/Rhesus macaque MLLT3/AF9 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP8842-Ag-1/ GM-Tg-felg-IP8842-Ag-2 | Feline MLLT3/AF9 protein | Feline |
| GM-Tg-cang-IP8842-Ag-1/ GM-Tg-cang-IP8842-Ag-2 | Canine MLLT3/AF9 protein | Canine |
| GM-Tg-bovg-IP8842-Ag-1/ GM-Tg-bovg-IP8842-Ag-2 | Bovine MLLT3/AF9 protein | Bovine |
| GM-Tg-equg-IP8842-Ag-1/ GM-Tg-equg-IP8842-Ag-2 | Equine MLLT3/AF9 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP8842-Ag-1/ GM-Tg-hg-IP8842-Ag-2;
GM-Tg-rg-IP8842-Ag-1/ GM-Tg-rg-IP8842-Ag-2;
GM-Tg-mg-IP8842-Ag-1/ GM-Tg-mg-IP8842-Ag-2; GM-Tg-cynog-IP8842-Ag-1/ GM-Tg-cynog-IP8842-Ag-2; GM-Tg-felg-IP8842-Ag-1/ GM-Tg-felg-IP8842-Ag-2; GM-Tg-cang-IP8842-Ag-1/ GM-Tg-cang-IP8842-Ag-2; GM-Tg-bovg-IP8842-Ag-1/ GM-Tg-bovg-IP8842-Ag-2; GM-Tg-equg-IP8842-Ag-1/ GM-Tg-equg-IP8842-Ag-2 |
| Products Name | MLLT3/AF9 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | MLLT3/AF9 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MLLT3/AF9 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.