Recombinant multi-species MBNL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MBNL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]
The Alternative Names of target: EXP,MBNL,MBNL1,Mbnl,Mbnl1,Muscleblind-like protein 1,Triplet-expansion RNA-binding protein,mKIAA0428

Target products collectionGo to MBNL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8809-Ag-1/ GM-Tg-hg-IP8809-Ag-2 Human MBNL1 protein Human
GM-Tg-rg-IP8809-Ag-1/ GM-Tg-rg-IP8809-Ag-2 Rat MBNL1 protein Rat
GM-Tg-mg-IP8809-Ag-1/ GM-Tg-mg-IP8809-Ag-2 Mouse MBNL1 protein Mouse
GM-Tg-cynog-IP8809-Ag-1/ GM-Tg-cynog-IP8809-Ag-2 Cynomolgus/Rhesus macaque MBNL1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8809-Ag-1/ GM-Tg-felg-IP8809-Ag-2 Feline MBNL1 protein Feline
GM-Tg-cang-IP8809-Ag-1/ GM-Tg-cang-IP8809-Ag-2 Canine MBNL1 protein Canine
GM-Tg-bovg-IP8809-Ag-1/ GM-Tg-bovg-IP8809-Ag-2 Bovine MBNL1 protein Bovine
GM-Tg-equg-IP8809-Ag-1/ GM-Tg-equg-IP8809-Ag-2 Equine MBNL1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8809-Ag-1/ GM-Tg-hg-IP8809-Ag-2; GM-Tg-rg-IP8809-Ag-1/ GM-Tg-rg-IP8809-Ag-2;
GM-Tg-mg-IP8809-Ag-1/ GM-Tg-mg-IP8809-Ag-2; GM-Tg-cynog-IP8809-Ag-1/ GM-Tg-cynog-IP8809-Ag-2;
GM-Tg-felg-IP8809-Ag-1/ GM-Tg-felg-IP8809-Ag-2; GM-Tg-cang-IP8809-Ag-1/ GM-Tg-cang-IP8809-Ag-2;
GM-Tg-bovg-IP8809-Ag-1/ GM-Tg-bovg-IP8809-Ag-2; GM-Tg-equg-IP8809-Ag-1/ GM-Tg-equg-IP8809-Ag-2
Products Name MBNL1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MBNL1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MBNL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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