Recombinant multi-species MAX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
The Alternative Names of target: Class D basic helix-loop-helix protein 4 (bHLHd4),MAX,Max,Myc-associated factor X,PDMCS,Protein max,bHLHd4,bHLHd5,bHLHd6,bHLHd7,bHLHd8

Target products collectionGo to MAX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8804-Ag-1/ GM-Tg-hg-IP8804-Ag-2 Human MAX protein Human
GM-Tg-rg-IP8804-Ag-1/ GM-Tg-rg-IP8804-Ag-2 Rat MAX protein Rat
GM-Tg-mg-IP8804-Ag-1/ GM-Tg-mg-IP8804-Ag-2 Mouse MAX protein Mouse
GM-Tg-cynog-IP8804-Ag-1/ GM-Tg-cynog-IP8804-Ag-2 Cynomolgus/Rhesus macaque MAX protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8804-Ag-1/ GM-Tg-felg-IP8804-Ag-2 Feline MAX protein Feline
GM-Tg-cang-IP8804-Ag-1/ GM-Tg-cang-IP8804-Ag-2 Canine MAX protein Canine
GM-Tg-bovg-IP8804-Ag-1/ GM-Tg-bovg-IP8804-Ag-2 Bovine MAX protein Bovine
GM-Tg-equg-IP8804-Ag-1/ GM-Tg-equg-IP8804-Ag-2 Equine MAX protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8804-Ag-1/ GM-Tg-hg-IP8804-Ag-2; GM-Tg-rg-IP8804-Ag-1/ GM-Tg-rg-IP8804-Ag-2;
GM-Tg-mg-IP8804-Ag-1/ GM-Tg-mg-IP8804-Ag-2; GM-Tg-cynog-IP8804-Ag-1/ GM-Tg-cynog-IP8804-Ag-2;
GM-Tg-felg-IP8804-Ag-1/ GM-Tg-felg-IP8804-Ag-2; GM-Tg-cang-IP8804-Ag-1/ GM-Tg-cang-IP8804-Ag-2;
GM-Tg-bovg-IP8804-Ag-1/ GM-Tg-bovg-IP8804-Ag-2; GM-Tg-equg-IP8804-Ag-1/ GM-Tg-equg-IP8804-Ag-2
Products Name MAX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MAX
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.