Recombinant multi-species MAD2L1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAD2L1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]
The Alternative Names of target: HSMAD2,HsMAD2,MAD2,MAD2L1,Mad2l1,Mitotic arrest deficient 2-like protein 1 (MAD2-like protein 1),Mitotic spindle assembly checkpoint protein MAD2A

Target products collectionGo to MAD2L1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8775-Ag-1/ GM-Tg-hg-IP8775-Ag-2 Human MAD2L1 protein Human
GM-Tg-rg-IP8775-Ag-1/ GM-Tg-rg-IP8775-Ag-2 Rat MAD2L1 protein Rat
GM-Tg-mg-IP8775-Ag-1/ GM-Tg-mg-IP8775-Ag-2 Mouse MAD2L1 protein Mouse
GM-Tg-cynog-IP8775-Ag-1/ GM-Tg-cynog-IP8775-Ag-2 Cynomolgus/Rhesus macaque MAD2L1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8775-Ag-1/ GM-Tg-felg-IP8775-Ag-2 Feline MAD2L1 protein Feline
GM-Tg-cang-IP8775-Ag-1/ GM-Tg-cang-IP8775-Ag-2 Canine MAD2L1 protein Canine
GM-Tg-bovg-IP8775-Ag-1/ GM-Tg-bovg-IP8775-Ag-2 Bovine MAD2L1 protein Bovine
GM-Tg-equg-IP8775-Ag-1/ GM-Tg-equg-IP8775-Ag-2 Equine MAD2L1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8775-Ag-1/ GM-Tg-hg-IP8775-Ag-2; GM-Tg-rg-IP8775-Ag-1/ GM-Tg-rg-IP8775-Ag-2;
GM-Tg-mg-IP8775-Ag-1/ GM-Tg-mg-IP8775-Ag-2; GM-Tg-cynog-IP8775-Ag-1/ GM-Tg-cynog-IP8775-Ag-2;
GM-Tg-felg-IP8775-Ag-1/ GM-Tg-felg-IP8775-Ag-2; GM-Tg-cang-IP8775-Ag-1/ GM-Tg-cang-IP8775-Ag-2;
GM-Tg-bovg-IP8775-Ag-1/ GM-Tg-bovg-IP8775-Ag-2; GM-Tg-equg-IP8775-Ag-1/ GM-Tg-equg-IP8775-Ag-2
Products Name MAD2L1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MAD2L1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAD2L1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.