Recombinant multi-species IRF4/MUM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IRF4/MUM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
The Alternative Names of target: IRF-4,IRF4,Interferon regulatory factor 4,Irf4,LSIRF,Lymphocyte-specific interferon regulatory factor (LSIRF),MUM1,Multiple myeloma oncogene 1,NF-EM5,SHEP8,Spip

Target products collectionGo to IRF4/MUM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8314-Ag-1/ GM-Tg-hg-IP8314-Ag-2 Human IRF4/MUM1 protein Human
GM-Tg-rg-IP8314-Ag-1/ GM-Tg-rg-IP8314-Ag-2 Rat IRF4/MUM1 protein Rat
GM-Tg-mg-IP8314-Ag-1/ GM-Tg-mg-IP8314-Ag-2 Mouse IRF4/MUM1 protein Mouse
GM-Tg-cynog-IP8314-Ag-1/ GM-Tg-cynog-IP8314-Ag-2 Cynomolgus/Rhesus macaque IRF4/MUM1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8314-Ag-1/ GM-Tg-felg-IP8314-Ag-2 Feline IRF4/MUM1 protein Feline
GM-Tg-cang-IP8314-Ag-1/ GM-Tg-cang-IP8314-Ag-2 Canine IRF4/MUM1 protein Canine
GM-Tg-bovg-IP8314-Ag-1/ GM-Tg-bovg-IP8314-Ag-2 Bovine IRF4/MUM1 protein Bovine
GM-Tg-equg-IP8314-Ag-1/ GM-Tg-equg-IP8314-Ag-2 Equine IRF4/MUM1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8314-Ag-1/ GM-Tg-hg-IP8314-Ag-2; GM-Tg-rg-IP8314-Ag-1/ GM-Tg-rg-IP8314-Ag-2;
GM-Tg-mg-IP8314-Ag-1/ GM-Tg-mg-IP8314-Ag-2; GM-Tg-cynog-IP8314-Ag-1/ GM-Tg-cynog-IP8314-Ag-2;
GM-Tg-felg-IP8314-Ag-1/ GM-Tg-felg-IP8314-Ag-2; GM-Tg-cang-IP8314-Ag-1/ GM-Tg-cang-IP8314-Ag-2;
GM-Tg-bovg-IP8314-Ag-1/ GM-Tg-bovg-IP8314-Ag-2; GM-Tg-equg-IP8314-Ag-1/ GM-Tg-equg-IP8314-Ag-2
Products Name IRF4/MUM1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IRF4/MUM1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IRF4/MUM1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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