Recombinant multi-species SP110 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SP110 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: IFI41,IFI75,IPR1,Interferon-induced protein 41/75,SP110,Sp110,Sp110 nuclear body protein,Speckled 110 kDa,Transcriptional coactivator Sp110,VODI

Target products collectionGo to SP110 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8184-Ag-1/ GM-Tg-hg-IP8184-Ag-2 Human SP110 protein Human
GM-Tg-rg-IP8184-Ag-1/ GM-Tg-rg-IP8184-Ag-2 Rat SP110 protein Rat
GM-Tg-mg-IP8184-Ag-1/ GM-Tg-mg-IP8184-Ag-2 Mouse SP110 protein Mouse
GM-Tg-cynog-IP8184-Ag-1/ GM-Tg-cynog-IP8184-Ag-2 Cynomolgus/Rhesus macaque SP110 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8184-Ag-1/ GM-Tg-felg-IP8184-Ag-2 Feline SP110 protein Feline
GM-Tg-cang-IP8184-Ag-1/ GM-Tg-cang-IP8184-Ag-2 Canine SP110 protein Canine
GM-Tg-bovg-IP8184-Ag-1/ GM-Tg-bovg-IP8184-Ag-2 Bovine SP110 protein Bovine
GM-Tg-equg-IP8184-Ag-1/ GM-Tg-equg-IP8184-Ag-2 Equine SP110 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8184-Ag-1/ GM-Tg-hg-IP8184-Ag-2; GM-Tg-rg-IP8184-Ag-1/ GM-Tg-rg-IP8184-Ag-2;
GM-Tg-mg-IP8184-Ag-1/ GM-Tg-mg-IP8184-Ag-2; GM-Tg-cynog-IP8184-Ag-1/ GM-Tg-cynog-IP8184-Ag-2;
GM-Tg-felg-IP8184-Ag-1/ GM-Tg-felg-IP8184-Ag-2; GM-Tg-cang-IP8184-Ag-1/ GM-Tg-cang-IP8184-Ag-2;
GM-Tg-bovg-IP8184-Ag-1/ GM-Tg-bovg-IP8184-Ag-2; GM-Tg-equg-IP8184-Ag-1/ GM-Tg-equg-IP8184-Ag-2
Products Name SP110 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SP110
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SP110 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.