Recombinant multi-species MMAB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMAB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found. [provided by RefSeq, Apr 2011]
The Alternative Names of target: 9130222L19Rik,ATP:co(I)rrinoid adenosyltransferase MMAB,ATR,CFAP23,Corrinoid adenosyltransferase MMAB,MMAB,Methylmalonic aciduria type B protein,Mmab,cblB,cob

Target products collectionGo to MMAB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP8032-Ag-1/ GM-Tg-hg-IP8032-Ag-2 Human MMAB protein Human
GM-Tg-rg-IP8032-Ag-1/ GM-Tg-rg-IP8032-Ag-2 Rat MMAB protein Rat
GM-Tg-mg-IP8032-Ag-1/ GM-Tg-mg-IP8032-Ag-2 Mouse MMAB protein Mouse
GM-Tg-cynog-IP8032-Ag-1/ GM-Tg-cynog-IP8032-Ag-2 Cynomolgus/Rhesus macaque MMAB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP8032-Ag-1/ GM-Tg-felg-IP8032-Ag-2 Feline MMAB protein Feline
GM-Tg-cang-IP8032-Ag-1/ GM-Tg-cang-IP8032-Ag-2 Canine MMAB protein Canine
GM-Tg-bovg-IP8032-Ag-1/ GM-Tg-bovg-IP8032-Ag-2 Bovine MMAB protein Bovine
GM-Tg-equg-IP8032-Ag-1/ GM-Tg-equg-IP8032-Ag-2 Equine MMAB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP8032-Ag-1/ GM-Tg-hg-IP8032-Ag-2; GM-Tg-rg-IP8032-Ag-1/ GM-Tg-rg-IP8032-Ag-2;
GM-Tg-mg-IP8032-Ag-1/ GM-Tg-mg-IP8032-Ag-2; GM-Tg-cynog-IP8032-Ag-1/ GM-Tg-cynog-IP8032-Ag-2;
GM-Tg-felg-IP8032-Ag-1/ GM-Tg-felg-IP8032-Ag-2; GM-Tg-cang-IP8032-Ag-1/ GM-Tg-cang-IP8032-Ag-2;
GM-Tg-bovg-IP8032-Ag-1/ GM-Tg-bovg-IP8032-Ag-2; GM-Tg-equg-IP8032-Ag-1/ GM-Tg-equg-IP8032-Ag-2
Products Name MMAB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MMAB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMAB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.