Recombinant multi-species HNRNPAB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNRNPAB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 3010025C11Rik,A1F-C1,ABBP1,APOBEC1-binding protein 1 (ABBP-1),CBF-A,Cgbf,Cgbfa,DBP40,HNRNP A/B,HNRNPAB,HNRPAB,Heterogeneous nuclear ribonucleoprotein A/B,Hnrnpab,Hnrpab,hnRNP A/B
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP7975-Ag-1/ GM-Tg-hg-IP7975-Ag-2 | Human HNRNPAB protein | Human |
| GM-Tg-rg-IP7975-Ag-1/ GM-Tg-rg-IP7975-Ag-2 | Rat HNRNPAB protein | Rat |
| GM-Tg-mg-IP7975-Ag-1/ GM-Tg-mg-IP7975-Ag-2 | Mouse HNRNPAB protein | Mouse |
| GM-Tg-cynog-IP7975-Ag-1/ GM-Tg-cynog-IP7975-Ag-2 | Cynomolgus/Rhesus macaque HNRNPAB protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP7975-Ag-1/ GM-Tg-felg-IP7975-Ag-2 | Feline HNRNPAB protein | Feline |
| GM-Tg-cang-IP7975-Ag-1/ GM-Tg-cang-IP7975-Ag-2 | Canine HNRNPAB protein | Canine |
| GM-Tg-bovg-IP7975-Ag-1/ GM-Tg-bovg-IP7975-Ag-2 | Bovine HNRNPAB protein | Bovine |
| GM-Tg-equg-IP7975-Ag-1/ GM-Tg-equg-IP7975-Ag-2 | Equine HNRNPAB protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP7975-Ag-1/ GM-Tg-hg-IP7975-Ag-2;
GM-Tg-rg-IP7975-Ag-1/ GM-Tg-rg-IP7975-Ag-2;
GM-Tg-mg-IP7975-Ag-1/ GM-Tg-mg-IP7975-Ag-2; GM-Tg-cynog-IP7975-Ag-1/ GM-Tg-cynog-IP7975-Ag-2; GM-Tg-felg-IP7975-Ag-1/ GM-Tg-felg-IP7975-Ag-2; GM-Tg-cang-IP7975-Ag-1/ GM-Tg-cang-IP7975-Ag-2; GM-Tg-bovg-IP7975-Ag-1/ GM-Tg-bovg-IP7975-Ag-2; GM-Tg-equg-IP7975-Ag-1/ GM-Tg-equg-IP7975-Ag-2 |
| Products Name | HNRNPAB protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | HNRNPAB |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNRNPAB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.