Recombinant multi-species HNRNPA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNRNPA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome. [provided by RefSeq, Feb 2016]
The Alternative Names of target: ALS19,ALS20,HCP-1,HDP-1,HNRNPA1,HNRPA1,HNRPA1L3,Hdp,Helix-destabilizing protein,Heterogeneous nuclear ribonucleoprotein A1,Hnrnpa1,Hnrpa1,IBMPFD3,MPD3,Single-strand RNA-binding protein,UP 1,hnRNP A1,hnRNP core protein A1,hnRNP-A1,hnrnp-A1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP7973-Ag-1/ GM-Tg-hg-IP7973-Ag-2 | Human HNRNPA1 protein | Human |
| GM-Tg-rg-IP7973-Ag-1/ GM-Tg-rg-IP7973-Ag-2 | Rat HNRNPA1 protein | Rat |
| GM-Tg-mg-IP7973-Ag-1/ GM-Tg-mg-IP7973-Ag-2 | Mouse HNRNPA1 protein | Mouse |
| GM-Tg-cynog-IP7973-Ag-1/ GM-Tg-cynog-IP7973-Ag-2 | Cynomolgus/Rhesus macaque HNRNPA1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP7973-Ag-1/ GM-Tg-felg-IP7973-Ag-2 | Feline HNRNPA1 protein | Feline |
| GM-Tg-cang-IP7973-Ag-1/ GM-Tg-cang-IP7973-Ag-2 | Canine HNRNPA1 protein | Canine |
| GM-Tg-bovg-IP7973-Ag-1/ GM-Tg-bovg-IP7973-Ag-2 | Bovine HNRNPA1 protein | Bovine |
| GM-Tg-equg-IP7973-Ag-1/ GM-Tg-equg-IP7973-Ag-2 | Equine HNRNPA1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP7973-Ag-1/ GM-Tg-hg-IP7973-Ag-2;
GM-Tg-rg-IP7973-Ag-1/ GM-Tg-rg-IP7973-Ag-2;
GM-Tg-mg-IP7973-Ag-1/ GM-Tg-mg-IP7973-Ag-2; GM-Tg-cynog-IP7973-Ag-1/ GM-Tg-cynog-IP7973-Ag-2; GM-Tg-felg-IP7973-Ag-1/ GM-Tg-felg-IP7973-Ag-2; GM-Tg-cang-IP7973-Ag-1/ GM-Tg-cang-IP7973-Ag-2; GM-Tg-bovg-IP7973-Ag-1/ GM-Tg-bovg-IP7973-Ag-2; GM-Tg-equg-IP7973-Ag-1/ GM-Tg-equg-IP7973-Ag-2 |
| Products Name | HNRNPA1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | HNRNPA1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNRNPA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.