Recombinant multi-species Hexokinase 1/HK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Hexokinase 1/HK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016]
The Alternative Names of target: Brain form hexokinase,CNSHA5,HEXOKIN,HK,HK1,HK1-ta,HK1-tb,HK1-tc,HKD,HKI,HMSNR,HXK1,Hexokinase 1,Hexokinase type I (HK I),Hexokinase-1,Hexokinase-A,Hk-1,Hk1,Hk1-s,NEDVIBA,NMSR,RP79,dea,hexokinase,mHk1-s
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP7939-Ag-1/ GM-Tg-hg-IP7939-Ag-2 | Human Hexokinase 1/HK1 protein | Human |
| GM-Tg-rg-IP7939-Ag-1/ GM-Tg-rg-IP7939-Ag-2 | Rat Hexokinase 1/HK1 protein | Rat |
| GM-Tg-mg-IP7939-Ag-1/ GM-Tg-mg-IP7939-Ag-2 | Mouse Hexokinase 1/HK1 protein | Mouse |
| GM-Tg-cynog-IP7939-Ag-1/ GM-Tg-cynog-IP7939-Ag-2 | Cynomolgus/Rhesus macaque Hexokinase 1/HK1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP7939-Ag-1/ GM-Tg-felg-IP7939-Ag-2 | Feline Hexokinase 1/HK1 protein | Feline |
| GM-Tg-cang-IP7939-Ag-1/ GM-Tg-cang-IP7939-Ag-2 | Canine Hexokinase 1/HK1 protein | Canine |
| GM-Tg-bovg-IP7939-Ag-1/ GM-Tg-bovg-IP7939-Ag-2 | Bovine Hexokinase 1/HK1 protein | Bovine |
| GM-Tg-equg-IP7939-Ag-1/ GM-Tg-equg-IP7939-Ag-2 | Equine Hexokinase 1/HK1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP7939-Ag-1/ GM-Tg-hg-IP7939-Ag-2;
GM-Tg-rg-IP7939-Ag-1/ GM-Tg-rg-IP7939-Ag-2;
GM-Tg-mg-IP7939-Ag-1/ GM-Tg-mg-IP7939-Ag-2; GM-Tg-cynog-IP7939-Ag-1/ GM-Tg-cynog-IP7939-Ag-2; GM-Tg-felg-IP7939-Ag-1/ GM-Tg-felg-IP7939-Ag-2; GM-Tg-cang-IP7939-Ag-1/ GM-Tg-cang-IP7939-Ag-2; GM-Tg-bovg-IP7939-Ag-1/ GM-Tg-bovg-IP7939-Ag-2; GM-Tg-equg-IP7939-Ag-1/ GM-Tg-equg-IP7939-Ag-2 |
| Products Name | Hexokinase 1/HK1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Hexokinase 1/HK1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Hexokinase 1/HK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.