Recombinant multi-species TAX1BP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TAX1BP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
The Alternative Names of target: 1300011C24Rik,Glutaminase-interacting protein 3,TAX1BP3,TIP-1,TIP1,Tax interaction protein 1 (TIP-1),Tax-interacting protein 1,Tax1-binding protein 3,Tax1bp3

Target products collectionGo to TAX1BP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7931-Ag-1/ GM-Tg-hg-IP7931-Ag-2 Human TAX1BP3 protein Human
GM-Tg-rg-IP7931-Ag-1/ GM-Tg-rg-IP7931-Ag-2 Rat TAX1BP3 protein Rat
GM-Tg-mg-IP7931-Ag-1/ GM-Tg-mg-IP7931-Ag-2 Mouse TAX1BP3 protein Mouse
GM-Tg-cynog-IP7931-Ag-1/ GM-Tg-cynog-IP7931-Ag-2 Cynomolgus/Rhesus macaque TAX1BP3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7931-Ag-1/ GM-Tg-felg-IP7931-Ag-2 Feline TAX1BP3 protein Feline
GM-Tg-cang-IP7931-Ag-1/ GM-Tg-cang-IP7931-Ag-2 Canine TAX1BP3 protein Canine
GM-Tg-bovg-IP7931-Ag-1/ GM-Tg-bovg-IP7931-Ag-2 Bovine TAX1BP3 protein Bovine
GM-Tg-equg-IP7931-Ag-1/ GM-Tg-equg-IP7931-Ag-2 Equine TAX1BP3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7931-Ag-1/ GM-Tg-hg-IP7931-Ag-2; GM-Tg-rg-IP7931-Ag-1/ GM-Tg-rg-IP7931-Ag-2;
GM-Tg-mg-IP7931-Ag-1/ GM-Tg-mg-IP7931-Ag-2; GM-Tg-cynog-IP7931-Ag-1/ GM-Tg-cynog-IP7931-Ag-2;
GM-Tg-felg-IP7931-Ag-1/ GM-Tg-felg-IP7931-Ag-2; GM-Tg-cang-IP7931-Ag-1/ GM-Tg-cang-IP7931-Ag-2;
GM-Tg-bovg-IP7931-Ag-1/ GM-Tg-bovg-IP7931-Ag-2; GM-Tg-equg-IP7931-Ag-1/ GM-Tg-equg-IP7931-Ag-2
Products Name TAX1BP3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TAX1BP3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TAX1BP3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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