Recombinant multi-species CTAG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CTAG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
The Alternative Names of target: Autoimmunogenic cancer/testis antigen NY-ESO-2,CAMEL,CT2,CT6.2,CT6.2a,CT6.2b,CTAG2,Cancer/testis antigen 2,Cancer/testis antigen 6.2 (CT6.2),ESO2,L antigen family member 1 (LAGE-1),LAGE-1,LAGE2B

Target products collectionGo to CTAG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7928-Ag-1/ GM-Tg-hg-IP7928-Ag-2 Human CTAG2 protein Human
GM-Tg-rg-IP7928-Ag-1/ GM-Tg-rg-IP7928-Ag-2 Rat CTAG2 protein Rat
GM-Tg-mg-IP7928-Ag-1/ GM-Tg-mg-IP7928-Ag-2 Mouse CTAG2 protein Mouse
GM-Tg-cynog-IP7928-Ag-1/ GM-Tg-cynog-IP7928-Ag-2 Cynomolgus/Rhesus macaque CTAG2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7928-Ag-1/ GM-Tg-felg-IP7928-Ag-2 Feline CTAG2 protein Feline
GM-Tg-cang-IP7928-Ag-1/ GM-Tg-cang-IP7928-Ag-2 Canine CTAG2 protein Canine
GM-Tg-bovg-IP7928-Ag-1/ GM-Tg-bovg-IP7928-Ag-2 Bovine CTAG2 protein Bovine
GM-Tg-equg-IP7928-Ag-1/ GM-Tg-equg-IP7928-Ag-2 Equine CTAG2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7928-Ag-1/ GM-Tg-hg-IP7928-Ag-2; GM-Tg-rg-IP7928-Ag-1/ GM-Tg-rg-IP7928-Ag-2;
GM-Tg-mg-IP7928-Ag-1/ GM-Tg-mg-IP7928-Ag-2; GM-Tg-cynog-IP7928-Ag-1/ GM-Tg-cynog-IP7928-Ag-2;
GM-Tg-felg-IP7928-Ag-1/ GM-Tg-felg-IP7928-Ag-2; GM-Tg-cang-IP7928-Ag-1/ GM-Tg-cang-IP7928-Ag-2;
GM-Tg-bovg-IP7928-Ag-1/ GM-Tg-bovg-IP7928-Ag-2; GM-Tg-equg-IP7928-Ag-1/ GM-Tg-equg-IP7928-Ag-2
Products Name CTAG2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CTAG2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CTAG2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.