Recombinant multi-species HELLS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HELLS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2014]
The Alternative Names of target: E130115I21Rik,HELLS,Hells,ICF4,LSH,Lymphoid-specific helicase,Lysh,Nbla10143,PASG,Proliferation-associated SNF2-like protein,SALNR,SMARCA6,SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6,YFK8

Target products collectionGo to HELLS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7917-Ag-1/ GM-Tg-hg-IP7917-Ag-2 Human HELLS protein Human
GM-Tg-rg-IP7917-Ag-1/ GM-Tg-rg-IP7917-Ag-2 Rat HELLS protein Rat
GM-Tg-mg-IP7917-Ag-1/ GM-Tg-mg-IP7917-Ag-2 Mouse HELLS protein Mouse
GM-Tg-cynog-IP7917-Ag-1/ GM-Tg-cynog-IP7917-Ag-2 Cynomolgus/Rhesus macaque HELLS protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7917-Ag-1/ GM-Tg-felg-IP7917-Ag-2 Feline HELLS protein Feline
GM-Tg-cang-IP7917-Ag-1/ GM-Tg-cang-IP7917-Ag-2 Canine HELLS protein Canine
GM-Tg-bovg-IP7917-Ag-1/ GM-Tg-bovg-IP7917-Ag-2 Bovine HELLS protein Bovine
GM-Tg-equg-IP7917-Ag-1/ GM-Tg-equg-IP7917-Ag-2 Equine HELLS protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7917-Ag-1/ GM-Tg-hg-IP7917-Ag-2; GM-Tg-rg-IP7917-Ag-1/ GM-Tg-rg-IP7917-Ag-2;
GM-Tg-mg-IP7917-Ag-1/ GM-Tg-mg-IP7917-Ag-2; GM-Tg-cynog-IP7917-Ag-1/ GM-Tg-cynog-IP7917-Ag-2;
GM-Tg-felg-IP7917-Ag-1/ GM-Tg-felg-IP7917-Ag-2; GM-Tg-cang-IP7917-Ag-1/ GM-Tg-cang-IP7917-Ag-2;
GM-Tg-bovg-IP7917-Ag-1/ GM-Tg-bovg-IP7917-Ag-2; GM-Tg-equg-IP7917-Ag-1/ GM-Tg-equg-IP7917-Ag-2
Products Name HELLS protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HELLS
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HELLS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.