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Recombinant multi-species Annexin A4/ANXA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Annexin A4/ANXA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
The Alternative Names of target: 35-beta calcimedin,AIV,ANX4,ANXA4,Annexin A4,Annexin IV,Annexin-4,Anx4,Anxa4,Carbohydrate-binding protein p33/p41,Chromobindin-4,Endonexin I,HEL-S-274,Lipocortin IV,P32.5,PAP-II,PIG28,PP4-X,Placental anticoagulant protein II (PAP-II),Protein II,Xanx-4,ZAP36
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MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP7916-Ag-1/ GM-Tg-hg-IP7916-Ag-2 | Human Annexin A4/ANXA4 protein | Human |
| GM-Tg-rg-IP7916-Ag-1/ GM-Tg-rg-IP7916-Ag-2 | Rat Annexin A4/ANXA4 protein | Rat |
| GM-Tg-mg-IP7916-Ag-1/ GM-Tg-mg-IP7916-Ag-2 | Mouse Annexin A4/ANXA4 protein | Mouse |
| GM-Tg-cynog-IP7916-Ag-1/ GM-Tg-cynog-IP7916-Ag-2 | Cynomolgus/Rhesus macaque Annexin A4/ANXA4 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP7916-Ag-1/ GM-Tg-felg-IP7916-Ag-2 | Feline Annexin A4/ANXA4 protein | Feline |
| GM-Tg-cang-IP7916-Ag-1/ GM-Tg-cang-IP7916-Ag-2 | Canine Annexin A4/ANXA4 protein | Canine |
| GM-Tg-bovg-IP7916-Ag-1/ GM-Tg-bovg-IP7916-Ag-2 | Bovine Annexin A4/ANXA4 protein | Bovine |
| GM-Tg-equg-IP7916-Ag-1/ GM-Tg-equg-IP7916-Ag-2 | Equine Annexin A4/ANXA4 protein | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP7916-Ag-1/ GM-Tg-hg-IP7916-Ag-2;
GM-Tg-rg-IP7916-Ag-1/ GM-Tg-rg-IP7916-Ag-2;
GM-Tg-mg-IP7916-Ag-1/ GM-Tg-mg-IP7916-Ag-2; GM-Tg-cynog-IP7916-Ag-1/ GM-Tg-cynog-IP7916-Ag-2; GM-Tg-felg-IP7916-Ag-1/ GM-Tg-felg-IP7916-Ag-2; GM-Tg-cang-IP7916-Ag-1/ GM-Tg-cang-IP7916-Ag-2; GM-Tg-bovg-IP7916-Ag-1/ GM-Tg-bovg-IP7916-Ag-2; GM-Tg-equg-IP7916-Ag-1/ GM-Tg-equg-IP7916-Ag-2 |
| Products Name | Annexin A4/ANXA4 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Annexin A4/ANXA4 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Annexin A4/ANXA4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.