Recombinant multi-species Hemoglobin/HBA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Hemoglobin/HBA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Alpha-globin,ECYT7,HBA-T3,HBA1,HBH,Hemoglobin,Hemoglobin alpha chain,Hemoglobin subunit alpha,METHBA

Target products collectionGo to Hemoglobin/HBA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7906-Ag-1/ GM-Tg-hg-IP7906-Ag-2 Human Hemoglobin/HBA1 protein Human
GM-Tg-rg-IP7906-Ag-1/ GM-Tg-rg-IP7906-Ag-2 Rat Hemoglobin/HBA1 protein Rat
GM-Tg-mg-IP7906-Ag-1/ GM-Tg-mg-IP7906-Ag-2 Mouse Hemoglobin/HBA1 protein Mouse
GM-Tg-cynog-IP7906-Ag-1/ GM-Tg-cynog-IP7906-Ag-2 Cynomolgus/Rhesus macaque Hemoglobin/HBA1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7906-Ag-1/ GM-Tg-felg-IP7906-Ag-2 Feline Hemoglobin/HBA1 protein Feline
GM-Tg-cang-IP7906-Ag-1/ GM-Tg-cang-IP7906-Ag-2 Canine Hemoglobin/HBA1 protein Canine
GM-Tg-bovg-IP7906-Ag-1/ GM-Tg-bovg-IP7906-Ag-2 Bovine Hemoglobin/HBA1 protein Bovine
GM-Tg-equg-IP7906-Ag-1/ GM-Tg-equg-IP7906-Ag-2 Equine Hemoglobin/HBA1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7906-Ag-1/ GM-Tg-hg-IP7906-Ag-2; GM-Tg-rg-IP7906-Ag-1/ GM-Tg-rg-IP7906-Ag-2;
GM-Tg-mg-IP7906-Ag-1/ GM-Tg-mg-IP7906-Ag-2; GM-Tg-cynog-IP7906-Ag-1/ GM-Tg-cynog-IP7906-Ag-2;
GM-Tg-felg-IP7906-Ag-1/ GM-Tg-felg-IP7906-Ag-2; GM-Tg-cang-IP7906-Ag-1/ GM-Tg-cang-IP7906-Ag-2;
GM-Tg-bovg-IP7906-Ag-1/ GM-Tg-bovg-IP7906-Ag-2; GM-Tg-equg-IP7906-Ag-1/ GM-Tg-equg-IP7906-Ag-2
Products Name Hemoglobin/HBA1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Hemoglobin/HBA1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Hemoglobin/HBA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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