Recombinant multi-species A1CF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine A1CF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
The Alternative Names of target: 1810073H04Rik,9130016M20Rik,A1CF,A1cf,A1cft,ACF,ACF64,ACF65,APOBEC1 complementation factor,APOBEC1-stimulating protein,APOBEC1CF,ASP,Acf,Apobec-1,MCM,MerCreMer,Tg(Myh6-cre/Esr1*)1Jmk,alpha-MHC-MerCreMer,alphaMHC-Cre-Mer-Cre,mer

Target products collectionGo to A1CF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7876-Ag-1/ GM-Tg-hg-IP7876-Ag-2 Human A1CF protein Human
GM-Tg-rg-IP7876-Ag-1/ GM-Tg-rg-IP7876-Ag-2 Rat A1CF protein Rat
GM-Tg-mg-IP7876-Ag-1/ GM-Tg-mg-IP7876-Ag-2 Mouse A1CF protein Mouse
GM-Tg-cynog-IP7876-Ag-1/ GM-Tg-cynog-IP7876-Ag-2 Cynomolgus/Rhesus macaque A1CF protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7876-Ag-1/ GM-Tg-felg-IP7876-Ag-2 Feline A1CF protein Feline
GM-Tg-cang-IP7876-Ag-1/ GM-Tg-cang-IP7876-Ag-2 Canine A1CF protein Canine
GM-Tg-bovg-IP7876-Ag-1/ GM-Tg-bovg-IP7876-Ag-2 Bovine A1CF protein Bovine
GM-Tg-equg-IP7876-Ag-1/ GM-Tg-equg-IP7876-Ag-2 Equine A1CF protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7876-Ag-1/ GM-Tg-hg-IP7876-Ag-2; GM-Tg-rg-IP7876-Ag-1/ GM-Tg-rg-IP7876-Ag-2;
GM-Tg-mg-IP7876-Ag-1/ GM-Tg-mg-IP7876-Ag-2; GM-Tg-cynog-IP7876-Ag-1/ GM-Tg-cynog-IP7876-Ag-2;
GM-Tg-felg-IP7876-Ag-1/ GM-Tg-felg-IP7876-Ag-2; GM-Tg-cang-IP7876-Ag-1/ GM-Tg-cang-IP7876-Ag-2;
GM-Tg-bovg-IP7876-Ag-1/ GM-Tg-bovg-IP7876-Ag-2; GM-Tg-equg-IP7876-Ag-1/ GM-Tg-equg-IP7876-Ag-2
Products Name A1CF protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name A1CF
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine A1CF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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