Recombinant multi-species NXT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NXT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1110001N02Rik,MTR2,NTF2-related export protein 1,NXT1,Nxt1,P15,Protein p15
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP7787-Ag-1/ GM-Tg-hg-IP7787-Ag-2 | Human NXT1 protein | Human |
| GM-Tg-rg-IP7787-Ag-1/ GM-Tg-rg-IP7787-Ag-2 | Rat NXT1 protein | Rat |
| GM-Tg-mg-IP7787-Ag-1/ GM-Tg-mg-IP7787-Ag-2 | Mouse NXT1 protein | Mouse |
| GM-Tg-cynog-IP7787-Ag-1/ GM-Tg-cynog-IP7787-Ag-2 | Cynomolgus/Rhesus macaque NXT1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP7787-Ag-1/ GM-Tg-felg-IP7787-Ag-2 | Feline NXT1 protein | Feline |
| GM-Tg-cang-IP7787-Ag-1/ GM-Tg-cang-IP7787-Ag-2 | Canine NXT1 protein | Canine |
| GM-Tg-bovg-IP7787-Ag-1/ GM-Tg-bovg-IP7787-Ag-2 | Bovine NXT1 protein | Bovine |
| GM-Tg-equg-IP7787-Ag-1/ GM-Tg-equg-IP7787-Ag-2 | Equine NXT1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP7787-Ag-1/ GM-Tg-hg-IP7787-Ag-2;
GM-Tg-rg-IP7787-Ag-1/ GM-Tg-rg-IP7787-Ag-2;
GM-Tg-mg-IP7787-Ag-1/ GM-Tg-mg-IP7787-Ag-2; GM-Tg-cynog-IP7787-Ag-1/ GM-Tg-cynog-IP7787-Ag-2; GM-Tg-felg-IP7787-Ag-1/ GM-Tg-felg-IP7787-Ag-2; GM-Tg-cang-IP7787-Ag-1/ GM-Tg-cang-IP7787-Ag-2; GM-Tg-bovg-IP7787-Ag-1/ GM-Tg-bovg-IP7787-Ag-2; GM-Tg-equg-IP7787-Ag-1/ GM-Tg-equg-IP7787-Ag-2 |
| Products Name | NXT1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | NXT1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NXT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.