Recombinant multi-species GNAI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GNAI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
The Alternative Names of target: Adenylate cyclase-inhibiting G alpha protein,BPGTPB,GNAI1,Gi,Gialpha1,Gnai-1,Gnai1,Guanine nucleotide-binding protein G(i) subunit alpha-1,HG1B,Hg1b,NEDHISB

Target products collectionGo to GNAI1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7521-Ag-1/ GM-Tg-hg-IP7521-Ag-2 Human GNAI1 protein Human
GM-Tg-rg-IP7521-Ag-1/ GM-Tg-rg-IP7521-Ag-2 Rat GNAI1 protein Rat
GM-Tg-mg-IP7521-Ag-1/ GM-Tg-mg-IP7521-Ag-2 Mouse GNAI1 protein Mouse
GM-Tg-cynog-IP7521-Ag-1/ GM-Tg-cynog-IP7521-Ag-2 Cynomolgus/Rhesus macaque GNAI1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7521-Ag-1/ GM-Tg-felg-IP7521-Ag-2 Feline GNAI1 protein Feline
GM-Tg-cang-IP7521-Ag-1/ GM-Tg-cang-IP7521-Ag-2 Canine GNAI1 protein Canine
GM-Tg-bovg-IP7521-Ag-1/ GM-Tg-bovg-IP7521-Ag-2 Bovine GNAI1 protein Bovine
GM-Tg-equg-IP7521-Ag-1/ GM-Tg-equg-IP7521-Ag-2 Equine GNAI1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7521-Ag-1/ GM-Tg-hg-IP7521-Ag-2; GM-Tg-rg-IP7521-Ag-1/ GM-Tg-rg-IP7521-Ag-2;
GM-Tg-mg-IP7521-Ag-1/ GM-Tg-mg-IP7521-Ag-2; GM-Tg-cynog-IP7521-Ag-1/ GM-Tg-cynog-IP7521-Ag-2;
GM-Tg-felg-IP7521-Ag-1/ GM-Tg-felg-IP7521-Ag-2; GM-Tg-cang-IP7521-Ag-1/ GM-Tg-cang-IP7521-Ag-2;
GM-Tg-bovg-IP7521-Ag-1/ GM-Tg-bovg-IP7521-Ag-2; GM-Tg-equg-IP7521-Ag-1/ GM-Tg-equg-IP7521-Ag-2
Products Name GNAI1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GNAI1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GNAI1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.