Recombinant multi-species VPS4A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VPS4A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 4930589C15Rik,CIMDAG,Protein SKD2,SKD1,SKD1A,SKD2,VPS4,VPS4-1,VPS4-1 (hVPS4),VPS4A,Vacuolar protein sorting-associated protein 4A,Vps4a

Target products collectionGo to VPS4A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7456-Ag-1/ GM-Tg-hg-IP7456-Ag-2 Human VPS4A protein Human
GM-Tg-rg-IP7456-Ag-1/ GM-Tg-rg-IP7456-Ag-2 Rat VPS4A protein Rat
GM-Tg-mg-IP7456-Ag-1/ GM-Tg-mg-IP7456-Ag-2 Mouse VPS4A protein Mouse
GM-Tg-cynog-IP7456-Ag-1/ GM-Tg-cynog-IP7456-Ag-2 Cynomolgus/Rhesus macaque VPS4A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7456-Ag-1/ GM-Tg-felg-IP7456-Ag-2 Feline VPS4A protein Feline
GM-Tg-cang-IP7456-Ag-1/ GM-Tg-cang-IP7456-Ag-2 Canine VPS4A protein Canine
GM-Tg-bovg-IP7456-Ag-1/ GM-Tg-bovg-IP7456-Ag-2 Bovine VPS4A protein Bovine
GM-Tg-equg-IP7456-Ag-1/ GM-Tg-equg-IP7456-Ag-2 Equine VPS4A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7456-Ag-1/ GM-Tg-hg-IP7456-Ag-2; GM-Tg-rg-IP7456-Ag-1/ GM-Tg-rg-IP7456-Ag-2;
GM-Tg-mg-IP7456-Ag-1/ GM-Tg-mg-IP7456-Ag-2; GM-Tg-cynog-IP7456-Ag-1/ GM-Tg-cynog-IP7456-Ag-2;
GM-Tg-felg-IP7456-Ag-1/ GM-Tg-felg-IP7456-Ag-2; GM-Tg-cang-IP7456-Ag-1/ GM-Tg-cang-IP7456-Ag-2;
GM-Tg-bovg-IP7456-Ag-1/ GM-Tg-bovg-IP7456-Ag-2; GM-Tg-equg-IP7456-Ag-1/ GM-Tg-equg-IP7456-Ag-2
Products Name VPS4A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name VPS4A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VPS4A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.