Recombinant multi-species DNAI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNAI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
The Alternative Names of target: 1110066F04Rik,Axonemal dynein intermediate chain 1,CILD1,DIC1,DNAI1,Dnai1,Dnaic1,Dynein axonemal intermediate chain 1,ICS1,PCD,b2b1526Clo,oda6

Target products collectionGo to DNAI1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7412-Ag-1/ GM-Tg-hg-IP7412-Ag-2 Human DNAI1 protein Human
GM-Tg-rg-IP7412-Ag-1/ GM-Tg-rg-IP7412-Ag-2 Rat DNAI1 protein Rat
GM-Tg-mg-IP7412-Ag-1/ GM-Tg-mg-IP7412-Ag-2 Mouse DNAI1 protein Mouse
GM-Tg-cynog-IP7412-Ag-1/ GM-Tg-cynog-IP7412-Ag-2 Cynomolgus/Rhesus macaque DNAI1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7412-Ag-1/ GM-Tg-felg-IP7412-Ag-2 Feline DNAI1 protein Feline
GM-Tg-cang-IP7412-Ag-1/ GM-Tg-cang-IP7412-Ag-2 Canine DNAI1 protein Canine
GM-Tg-bovg-IP7412-Ag-1/ GM-Tg-bovg-IP7412-Ag-2 Bovine DNAI1 protein Bovine
GM-Tg-equg-IP7412-Ag-1/ GM-Tg-equg-IP7412-Ag-2 Equine DNAI1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7412-Ag-1/ GM-Tg-hg-IP7412-Ag-2; GM-Tg-rg-IP7412-Ag-1/ GM-Tg-rg-IP7412-Ag-2;
GM-Tg-mg-IP7412-Ag-1/ GM-Tg-mg-IP7412-Ag-2; GM-Tg-cynog-IP7412-Ag-1/ GM-Tg-cynog-IP7412-Ag-2;
GM-Tg-felg-IP7412-Ag-1/ GM-Tg-felg-IP7412-Ag-2; GM-Tg-cang-IP7412-Ag-1/ GM-Tg-cang-IP7412-Ag-2;
GM-Tg-bovg-IP7412-Ag-1/ GM-Tg-bovg-IP7412-Ag-2; GM-Tg-equg-IP7412-Ag-1/ GM-Tg-equg-IP7412-Ag-2
Products Name DNAI1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DNAI1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNAI1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.