Recombinant multi-species GABPA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GABPA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]
The Alternative Names of target: E4TF1-60,E4TF1A,GA-binding protein alpha chain,GABP subunit alpha,GABPA,GABPalpha,Gabpa,NFT2,NRF2,NRF2A,Nrf-2alpha,Nrf2a,Nuclear respiratory factor 2 subunit alpha,RCH04A07,Transcription factor E4TF1-60

Target products collectionGo to GABPA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP7054-Ag-1/ GM-Tg-hg-IP7054-Ag-2 Human GABPA protein Human
GM-Tg-rg-IP7054-Ag-1/ GM-Tg-rg-IP7054-Ag-2 Rat GABPA protein Rat
GM-Tg-mg-IP7054-Ag-1/ GM-Tg-mg-IP7054-Ag-2 Mouse GABPA protein Mouse
GM-Tg-cynog-IP7054-Ag-1/ GM-Tg-cynog-IP7054-Ag-2 Cynomolgus/Rhesus macaque GABPA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP7054-Ag-1/ GM-Tg-felg-IP7054-Ag-2 Feline GABPA protein Feline
GM-Tg-cang-IP7054-Ag-1/ GM-Tg-cang-IP7054-Ag-2 Canine GABPA protein Canine
GM-Tg-bovg-IP7054-Ag-1/ GM-Tg-bovg-IP7054-Ag-2 Bovine GABPA protein Bovine
GM-Tg-equg-IP7054-Ag-1/ GM-Tg-equg-IP7054-Ag-2 Equine GABPA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP7054-Ag-1/ GM-Tg-hg-IP7054-Ag-2; GM-Tg-rg-IP7054-Ag-1/ GM-Tg-rg-IP7054-Ag-2;
GM-Tg-mg-IP7054-Ag-1/ GM-Tg-mg-IP7054-Ag-2; GM-Tg-cynog-IP7054-Ag-1/ GM-Tg-cynog-IP7054-Ag-2;
GM-Tg-felg-IP7054-Ag-1/ GM-Tg-felg-IP7054-Ag-2; GM-Tg-cang-IP7054-Ag-1/ GM-Tg-cang-IP7054-Ag-2;
GM-Tg-bovg-IP7054-Ag-1/ GM-Tg-bovg-IP7054-Ag-2; GM-Tg-equg-IP7054-Ag-1/ GM-Tg-equg-IP7054-Ag-2
Products Name GABPA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GABPA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GABPA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.