Recombinant multi-species GADD34/PPP1R15A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GADD34/PPP1R15A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 9630030H21,GADD34,Gadd34,Growth arrest and DNA damage-inducible protein GADD34,Myd116,Myeloid differentiation primary response protein MyD116 homolog,PPP1R15A,Peg-3,Ppp1r15a,Protein phosphatase 1 regulatory subunit 15A,RGD1624209

Target products collectionGo to GADD34/PPP1R15A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6960-Ag-1/ GM-Tg-hg-IP6960-Ag-2 Human GADD34/PPP1R15A protein Human
GM-Tg-rg-IP6960-Ag-1/ GM-Tg-rg-IP6960-Ag-2 Rat GADD34/PPP1R15A protein Rat
GM-Tg-mg-IP6960-Ag-1/ GM-Tg-mg-IP6960-Ag-2 Mouse GADD34/PPP1R15A protein Mouse
GM-Tg-cynog-IP6960-Ag-1/ GM-Tg-cynog-IP6960-Ag-2 Cynomolgus/Rhesus macaque GADD34/PPP1R15A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6960-Ag-1/ GM-Tg-felg-IP6960-Ag-2 Feline GADD34/PPP1R15A protein Feline
GM-Tg-cang-IP6960-Ag-1/ GM-Tg-cang-IP6960-Ag-2 Canine GADD34/PPP1R15A protein Canine
GM-Tg-bovg-IP6960-Ag-1/ GM-Tg-bovg-IP6960-Ag-2 Bovine GADD34/PPP1R15A protein Bovine
GM-Tg-equg-IP6960-Ag-1/ GM-Tg-equg-IP6960-Ag-2 Equine GADD34/PPP1R15A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6960-Ag-1/ GM-Tg-hg-IP6960-Ag-2; GM-Tg-rg-IP6960-Ag-1/ GM-Tg-rg-IP6960-Ag-2;
GM-Tg-mg-IP6960-Ag-1/ GM-Tg-mg-IP6960-Ag-2; GM-Tg-cynog-IP6960-Ag-1/ GM-Tg-cynog-IP6960-Ag-2;
GM-Tg-felg-IP6960-Ag-1/ GM-Tg-felg-IP6960-Ag-2; GM-Tg-cang-IP6960-Ag-1/ GM-Tg-cang-IP6960-Ag-2;
GM-Tg-bovg-IP6960-Ag-1/ GM-Tg-bovg-IP6960-Ag-2; GM-Tg-equg-IP6960-Ag-1/ GM-Tg-equg-IP6960-Ag-2
Products Name GADD34/PPP1R15A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GADD34/PPP1R15A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GADD34/PPP1R15A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.