Recombinant multi-species SASH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SASH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016]
The Alternative Names of target: 1100001C18Rik,2500002E12Rik,A330076K04Rik,CAPOK,DUH,DUH1,Proline-glutamate repeat-containing protein,RGD1566017,SAM and SH3 domain-containing protein 1,SASH1,SH3D6A,Sash1,dJ323M4.1,mKIAA0790

Target products collectionGo to SASH1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6834-Ag-1/ GM-Tg-hg-IP6834-Ag-2 Human SASH1 protein Human
GM-Tg-rg-IP6834-Ag-1/ GM-Tg-rg-IP6834-Ag-2 Rat SASH1 protein Rat
GM-Tg-mg-IP6834-Ag-1/ GM-Tg-mg-IP6834-Ag-2 Mouse SASH1 protein Mouse
GM-Tg-cynog-IP6834-Ag-1/ GM-Tg-cynog-IP6834-Ag-2 Cynomolgus/Rhesus macaque SASH1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6834-Ag-1/ GM-Tg-felg-IP6834-Ag-2 Feline SASH1 protein Feline
GM-Tg-cang-IP6834-Ag-1/ GM-Tg-cang-IP6834-Ag-2 Canine SASH1 protein Canine
GM-Tg-bovg-IP6834-Ag-1/ GM-Tg-bovg-IP6834-Ag-2 Bovine SASH1 protein Bovine
GM-Tg-equg-IP6834-Ag-1/ GM-Tg-equg-IP6834-Ag-2 Equine SASH1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6834-Ag-1/ GM-Tg-hg-IP6834-Ag-2; GM-Tg-rg-IP6834-Ag-1/ GM-Tg-rg-IP6834-Ag-2;
GM-Tg-mg-IP6834-Ag-1/ GM-Tg-mg-IP6834-Ag-2; GM-Tg-cynog-IP6834-Ag-1/ GM-Tg-cynog-IP6834-Ag-2;
GM-Tg-felg-IP6834-Ag-1/ GM-Tg-felg-IP6834-Ag-2; GM-Tg-cang-IP6834-Ag-1/ GM-Tg-cang-IP6834-Ag-2;
GM-Tg-bovg-IP6834-Ag-1/ GM-Tg-bovg-IP6834-Ag-2; GM-Tg-equg-IP6834-Ag-1/ GM-Tg-equg-IP6834-Ag-2
Products Name SASH1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SASH1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SASH1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.