Recombinant multi-species FOXO3A/FOXO3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FOXO3A/FOXO3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1110048B16Rik,2010203A17Rik,AF6q21,AF6q21 protein,FKHRL1,FKHRL1P2,FOXO-3,FOXO2,FOXO3,FOXO3A,Fkhr2,Fkhrl1,Forkhead box protein O3,Forkhead in rhabdomyosarcoma-like 1,Foxo3,Foxo3a
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP6719-Ag-1/ GM-Tg-hg-IP6719-Ag-2 | Human FOXO3A/FOXO3 protein | Human |
| GM-Tg-rg-IP6719-Ag-1/ GM-Tg-rg-IP6719-Ag-2 | Rat FOXO3A/FOXO3 protein | Rat |
| GM-Tg-mg-IP6719-Ag-1/ GM-Tg-mg-IP6719-Ag-2 | Mouse FOXO3A/FOXO3 protein | Mouse |
| GM-Tg-cynog-IP6719-Ag-1/ GM-Tg-cynog-IP6719-Ag-2 | Cynomolgus/Rhesus macaque FOXO3A/FOXO3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP6719-Ag-1/ GM-Tg-felg-IP6719-Ag-2 | Feline FOXO3A/FOXO3 protein | Feline |
| GM-Tg-cang-IP6719-Ag-1/ GM-Tg-cang-IP6719-Ag-2 | Canine FOXO3A/FOXO3 protein | Canine |
| GM-Tg-bovg-IP6719-Ag-1/ GM-Tg-bovg-IP6719-Ag-2 | Bovine FOXO3A/FOXO3 protein | Bovine |
| GM-Tg-equg-IP6719-Ag-1/ GM-Tg-equg-IP6719-Ag-2 | Equine FOXO3A/FOXO3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP6719-Ag-1/ GM-Tg-hg-IP6719-Ag-2;
GM-Tg-rg-IP6719-Ag-1/ GM-Tg-rg-IP6719-Ag-2;
GM-Tg-mg-IP6719-Ag-1/ GM-Tg-mg-IP6719-Ag-2; GM-Tg-cynog-IP6719-Ag-1/ GM-Tg-cynog-IP6719-Ag-2; GM-Tg-felg-IP6719-Ag-1/ GM-Tg-felg-IP6719-Ag-2; GM-Tg-cang-IP6719-Ag-1/ GM-Tg-cang-IP6719-Ag-2; GM-Tg-bovg-IP6719-Ag-1/ GM-Tg-bovg-IP6719-Ag-2; GM-Tg-equg-IP6719-Ag-1/ GM-Tg-equg-IP6719-Ag-2 |
| Products Name | FOXO3A/FOXO3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | FOXO3A/FOXO3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FOXO3A/FOXO3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.