Recombinant multi-species KDM4B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KDM4B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Enables histone H3K36 demethylase activity and histone H3K9me2/H3K9me3 demethylase activity. Predicted to be involved in brain development; chromatin remodeling; and regulation of gene expression. Located in cytosol and nucleoplasm. Implicated in autosomal dominant intellectual developmental disorder; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer. [provided by Alliance of Genome Resources, Feb 2025]
The Alternative Names of target: 4732474L06Rik,JMJD2B,JmjC domain-containing histone demethylation protein 3B,Jmjd2b,Jumonji domain-containing protein 2B,KDM4B,Kdm4b,Lysine-specific demethylase 4B,MRD65,TDRD14B,[histone H3]-trimethyl-L-lysine(9) demethylase 4B

Target products collectionGo to KDM4B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6687-Ag-1/ GM-Tg-hg-IP6687-Ag-2 Human KDM4B protein Human
GM-Tg-rg-IP6687-Ag-1/ GM-Tg-rg-IP6687-Ag-2 Rat KDM4B protein Rat
GM-Tg-mg-IP6687-Ag-1/ GM-Tg-mg-IP6687-Ag-2 Mouse KDM4B protein Mouse
GM-Tg-cynog-IP6687-Ag-1/ GM-Tg-cynog-IP6687-Ag-2 Cynomolgus/Rhesus macaque KDM4B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6687-Ag-1/ GM-Tg-felg-IP6687-Ag-2 Feline KDM4B protein Feline
GM-Tg-cang-IP6687-Ag-1/ GM-Tg-cang-IP6687-Ag-2 Canine KDM4B protein Canine
GM-Tg-bovg-IP6687-Ag-1/ GM-Tg-bovg-IP6687-Ag-2 Bovine KDM4B protein Bovine
GM-Tg-equg-IP6687-Ag-1/ GM-Tg-equg-IP6687-Ag-2 Equine KDM4B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6687-Ag-1/ GM-Tg-hg-IP6687-Ag-2; GM-Tg-rg-IP6687-Ag-1/ GM-Tg-rg-IP6687-Ag-2;
GM-Tg-mg-IP6687-Ag-1/ GM-Tg-mg-IP6687-Ag-2; GM-Tg-cynog-IP6687-Ag-1/ GM-Tg-cynog-IP6687-Ag-2;
GM-Tg-felg-IP6687-Ag-1/ GM-Tg-felg-IP6687-Ag-2; GM-Tg-cang-IP6687-Ag-1/ GM-Tg-cang-IP6687-Ag-2;
GM-Tg-bovg-IP6687-Ag-1/ GM-Tg-bovg-IP6687-Ag-2; GM-Tg-equg-IP6687-Ag-1/ GM-Tg-equg-IP6687-Ag-2
Products Name KDM4B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KDM4B
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KDM4B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.