Recombinant multi-species SNRNP200 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SNRNP200 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]
The Alternative Names of target: A330064G03Rik,ASCC3L1,Activating signal cointegrator 1 complex subunit 3-like 1,Ascc3l1,BRR2,BRR2 homolog,HELIC2,RP33,SNRNP200,Snrnp200,U5 small nuclear ribonucleoprotein 200 kDa helicase,U5 snRNP-specific 200 kDa protein (U5-200KD),U5-200-KD,U5-200KD
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP6682-Ag-1/ GM-Tg-hg-IP6682-Ag-2 | Human SNRNP200 protein | Human |
| GM-Tg-rg-IP6682-Ag-1/ GM-Tg-rg-IP6682-Ag-2 | Rat SNRNP200 protein | Rat |
| GM-Tg-mg-IP6682-Ag-1/ GM-Tg-mg-IP6682-Ag-2 | Mouse SNRNP200 protein | Mouse |
| GM-Tg-cynog-IP6682-Ag-1/ GM-Tg-cynog-IP6682-Ag-2 | Cynomolgus/Rhesus macaque SNRNP200 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP6682-Ag-1/ GM-Tg-felg-IP6682-Ag-2 | Feline SNRNP200 protein | Feline |
| GM-Tg-cang-IP6682-Ag-1/ GM-Tg-cang-IP6682-Ag-2 | Canine SNRNP200 protein | Canine |
| GM-Tg-bovg-IP6682-Ag-1/ GM-Tg-bovg-IP6682-Ag-2 | Bovine SNRNP200 protein | Bovine |
| GM-Tg-equg-IP6682-Ag-1/ GM-Tg-equg-IP6682-Ag-2 | Equine SNRNP200 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP6682-Ag-1/ GM-Tg-hg-IP6682-Ag-2;
GM-Tg-rg-IP6682-Ag-1/ GM-Tg-rg-IP6682-Ag-2;
GM-Tg-mg-IP6682-Ag-1/ GM-Tg-mg-IP6682-Ag-2; GM-Tg-cynog-IP6682-Ag-1/ GM-Tg-cynog-IP6682-Ag-2; GM-Tg-felg-IP6682-Ag-1/ GM-Tg-felg-IP6682-Ag-2; GM-Tg-cang-IP6682-Ag-1/ GM-Tg-cang-IP6682-Ag-2; GM-Tg-bovg-IP6682-Ag-1/ GM-Tg-bovg-IP6682-Ag-2; GM-Tg-equg-IP6682-Ag-1/ GM-Tg-equg-IP6682-Ag-2 |
| Products Name | SNRNP200 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | SNRNP200 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SNRNP200 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.