Recombinant multi-species EB1/MAPRE1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EB1/MAPRE1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5530600P05Rik,APC-binding protein EB1,BIM1p,D2Ertd459e,EB1,Eb1,End-binding protein 1 (EB1),MAPRE1,Mapre1,Microtubule-associated protein RP/EB family member 1

Target products collectionGo to EB1/MAPRE1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6636-Ag-1/ GM-Tg-hg-IP6636-Ag-2 Human EB1/MAPRE1 protein Human
GM-Tg-rg-IP6636-Ag-1/ GM-Tg-rg-IP6636-Ag-2 Rat EB1/MAPRE1 protein Rat
GM-Tg-mg-IP6636-Ag-1/ GM-Tg-mg-IP6636-Ag-2 Mouse EB1/MAPRE1 protein Mouse
GM-Tg-cynog-IP6636-Ag-1/ GM-Tg-cynog-IP6636-Ag-2 Cynomolgus/Rhesus macaque EB1/MAPRE1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6636-Ag-1/ GM-Tg-felg-IP6636-Ag-2 Feline EB1/MAPRE1 protein Feline
GM-Tg-cang-IP6636-Ag-1/ GM-Tg-cang-IP6636-Ag-2 Canine EB1/MAPRE1 protein Canine
GM-Tg-bovg-IP6636-Ag-1/ GM-Tg-bovg-IP6636-Ag-2 Bovine EB1/MAPRE1 protein Bovine
GM-Tg-equg-IP6636-Ag-1/ GM-Tg-equg-IP6636-Ag-2 Equine EB1/MAPRE1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6636-Ag-1/ GM-Tg-hg-IP6636-Ag-2; GM-Tg-rg-IP6636-Ag-1/ GM-Tg-rg-IP6636-Ag-2;
GM-Tg-mg-IP6636-Ag-1/ GM-Tg-mg-IP6636-Ag-2; GM-Tg-cynog-IP6636-Ag-1/ GM-Tg-cynog-IP6636-Ag-2;
GM-Tg-felg-IP6636-Ag-1/ GM-Tg-felg-IP6636-Ag-2; GM-Tg-cang-IP6636-Ag-1/ GM-Tg-cang-IP6636-Ag-2;
GM-Tg-bovg-IP6636-Ag-1/ GM-Tg-bovg-IP6636-Ag-2; GM-Tg-equg-IP6636-Ag-1/ GM-Tg-equg-IP6636-Ag-2
Products Name EB1/MAPRE1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name EB1/MAPRE1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EB1/MAPRE1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.