Recombinant multi-species MRAS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MRAS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
The Alternative Names of target: 2900078C09Rik,M-RAs,MRAS,Mras,NS11,R-RAS3,RRAS3,Ras-related protein M-Ras,Ras-related protein R-Ras3

Target products collectionGo to MRAS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6575-Ag-1/ GM-Tg-hg-IP6575-Ag-2 Human MRAS protein Human
GM-Tg-rg-IP6575-Ag-1/ GM-Tg-rg-IP6575-Ag-2 Rat MRAS protein Rat
GM-Tg-mg-IP6575-Ag-1/ GM-Tg-mg-IP6575-Ag-2 Mouse MRAS protein Mouse
GM-Tg-cynog-IP6575-Ag-1/ GM-Tg-cynog-IP6575-Ag-2 Cynomolgus/Rhesus macaque MRAS protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6575-Ag-1/ GM-Tg-felg-IP6575-Ag-2 Feline MRAS protein Feline
GM-Tg-cang-IP6575-Ag-1/ GM-Tg-cang-IP6575-Ag-2 Canine MRAS protein Canine
GM-Tg-bovg-IP6575-Ag-1/ GM-Tg-bovg-IP6575-Ag-2 Bovine MRAS protein Bovine
GM-Tg-equg-IP6575-Ag-1/ GM-Tg-equg-IP6575-Ag-2 Equine MRAS protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6575-Ag-1/ GM-Tg-hg-IP6575-Ag-2; GM-Tg-rg-IP6575-Ag-1/ GM-Tg-rg-IP6575-Ag-2;
GM-Tg-mg-IP6575-Ag-1/ GM-Tg-mg-IP6575-Ag-2; GM-Tg-cynog-IP6575-Ag-1/ GM-Tg-cynog-IP6575-Ag-2;
GM-Tg-felg-IP6575-Ag-1/ GM-Tg-felg-IP6575-Ag-2; GM-Tg-cang-IP6575-Ag-1/ GM-Tg-cang-IP6575-Ag-2;
GM-Tg-bovg-IP6575-Ag-1/ GM-Tg-bovg-IP6575-Ag-2; GM-Tg-equg-IP6575-Ag-1/ GM-Tg-equg-IP6575-Ag-2
Products Name MRAS protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MRAS
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MRAS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.