Recombinant multi-species ALDOA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALDOA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
The Alternative Names of target: ALDA,ALDOA,Aldo-1,Aldo1,Aldoa,Fructose-bisphosphate aldolase A,GSD12,HEL-S-87p,Lung cancer antigen NY-LU-1,Muscle-type aldolase,RNALDOG5
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP6566-Ag-1/ GM-Tg-hg-IP6566-Ag-2 | Human ALDOA protein | Human |
| GM-Tg-rg-IP6566-Ag-1/ GM-Tg-rg-IP6566-Ag-2 | Rat ALDOA protein | Rat |
| GM-Tg-mg-IP6566-Ag-1/ GM-Tg-mg-IP6566-Ag-2 | Mouse ALDOA protein | Mouse |
| GM-Tg-cynog-IP6566-Ag-1/ GM-Tg-cynog-IP6566-Ag-2 | Cynomolgus/Rhesus macaque ALDOA protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP6566-Ag-1/ GM-Tg-felg-IP6566-Ag-2 | Feline ALDOA protein | Feline |
| GM-Tg-cang-IP6566-Ag-1/ GM-Tg-cang-IP6566-Ag-2 | Canine ALDOA protein | Canine |
| GM-Tg-bovg-IP6566-Ag-1/ GM-Tg-bovg-IP6566-Ag-2 | Bovine ALDOA protein | Bovine |
| GM-Tg-equg-IP6566-Ag-1/ GM-Tg-equg-IP6566-Ag-2 | Equine ALDOA protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP6566-Ag-1/ GM-Tg-hg-IP6566-Ag-2;
GM-Tg-rg-IP6566-Ag-1/ GM-Tg-rg-IP6566-Ag-2;
GM-Tg-mg-IP6566-Ag-1/ GM-Tg-mg-IP6566-Ag-2; GM-Tg-cynog-IP6566-Ag-1/ GM-Tg-cynog-IP6566-Ag-2; GM-Tg-felg-IP6566-Ag-1/ GM-Tg-felg-IP6566-Ag-2; GM-Tg-cang-IP6566-Ag-1/ GM-Tg-cang-IP6566-Ag-2; GM-Tg-bovg-IP6566-Ag-1/ GM-Tg-bovg-IP6566-Ag-2; GM-Tg-equg-IP6566-Ag-1/ GM-Tg-equg-IP6566-Ag-2 |
| Products Name | ALDOA protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ALDOA |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALDOA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.