Recombinant multi-species ETV1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ETV1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2016]
The Alternative Names of target: ER81,ETS translocation variant 1,ETV1,Ets-related protein 81,Etsrp81,Etv1

Target products collectionGo to ETV1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6440-Ag-1/ GM-Tg-hg-IP6440-Ag-2 Human ETV1 protein Human
GM-Tg-rg-IP6440-Ag-1/ GM-Tg-rg-IP6440-Ag-2 Rat ETV1 protein Rat
GM-Tg-mg-IP6440-Ag-1/ GM-Tg-mg-IP6440-Ag-2 Mouse ETV1 protein Mouse
GM-Tg-cynog-IP6440-Ag-1/ GM-Tg-cynog-IP6440-Ag-2 Cynomolgus/Rhesus macaque ETV1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6440-Ag-1/ GM-Tg-felg-IP6440-Ag-2 Feline ETV1 protein Feline
GM-Tg-cang-IP6440-Ag-1/ GM-Tg-cang-IP6440-Ag-2 Canine ETV1 protein Canine
GM-Tg-bovg-IP6440-Ag-1/ GM-Tg-bovg-IP6440-Ag-2 Bovine ETV1 protein Bovine
GM-Tg-equg-IP6440-Ag-1/ GM-Tg-equg-IP6440-Ag-2 Equine ETV1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6440-Ag-1/ GM-Tg-hg-IP6440-Ag-2; GM-Tg-rg-IP6440-Ag-1/ GM-Tg-rg-IP6440-Ag-2;
GM-Tg-mg-IP6440-Ag-1/ GM-Tg-mg-IP6440-Ag-2; GM-Tg-cynog-IP6440-Ag-1/ GM-Tg-cynog-IP6440-Ag-2;
GM-Tg-felg-IP6440-Ag-1/ GM-Tg-felg-IP6440-Ag-2; GM-Tg-cang-IP6440-Ag-1/ GM-Tg-cang-IP6440-Ag-2;
GM-Tg-bovg-IP6440-Ag-1/ GM-Tg-bovg-IP6440-Ag-2; GM-Tg-equg-IP6440-Ag-1/ GM-Tg-equg-IP6440-Ag-2
Products Name ETV1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ETV1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ETV1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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