Recombinant multi-species ERCC3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ERCC3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
The Alternative Names of target: BTF2,BTF2 p89,Basic transcription factor 2 89 kDa subunit (BTF2 p89),DNA 3'-5' helicase/translocase XPB,DNA excision repair protein ERCC-3,DNA repair protein complementing XP-B cells,ERCC3,Ercc-3,Ercc3,GTF2H,General transcription and DNA repair factor IIH helicase/translocase subunit XPB,RAD25,Ssl2,TFIIH,TFIIH basal transcription factor complex 89 kDa subunit (TFIIH 89 kDa subunit,TFIIH p89),TFIIH subunit XPB,TTD2,XPB,Xeroderma pigmentosum group B-complementing protein

Target products collectionGo to ERCC3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6427-Ag-1/ GM-Tg-hg-IP6427-Ag-2 Human ERCC3 protein Human
GM-Tg-rg-IP6427-Ag-1/ GM-Tg-rg-IP6427-Ag-2 Rat ERCC3 protein Rat
GM-Tg-mg-IP6427-Ag-1/ GM-Tg-mg-IP6427-Ag-2 Mouse ERCC3 protein Mouse
GM-Tg-cynog-IP6427-Ag-1/ GM-Tg-cynog-IP6427-Ag-2 Cynomolgus/Rhesus macaque ERCC3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6427-Ag-1/ GM-Tg-felg-IP6427-Ag-2 Feline ERCC3 protein Feline
GM-Tg-cang-IP6427-Ag-1/ GM-Tg-cang-IP6427-Ag-2 Canine ERCC3 protein Canine
GM-Tg-bovg-IP6427-Ag-1/ GM-Tg-bovg-IP6427-Ag-2 Bovine ERCC3 protein Bovine
GM-Tg-equg-IP6427-Ag-1/ GM-Tg-equg-IP6427-Ag-2 Equine ERCC3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6427-Ag-1/ GM-Tg-hg-IP6427-Ag-2; GM-Tg-rg-IP6427-Ag-1/ GM-Tg-rg-IP6427-Ag-2;
GM-Tg-mg-IP6427-Ag-1/ GM-Tg-mg-IP6427-Ag-2; GM-Tg-cynog-IP6427-Ag-1/ GM-Tg-cynog-IP6427-Ag-2;
GM-Tg-felg-IP6427-Ag-1/ GM-Tg-felg-IP6427-Ag-2; GM-Tg-cang-IP6427-Ag-1/ GM-Tg-cang-IP6427-Ag-2;
GM-Tg-bovg-IP6427-Ag-1/ GM-Tg-bovg-IP6427-Ag-2; GM-Tg-equg-IP6427-Ag-1/ GM-Tg-equg-IP6427-Ag-2
Products Name ERCC3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ERCC3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ERCC3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.