Recombinant multi-species ZNF384 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ZNF384 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
The Alternative Names of target: C130073D16Rik,CAG repeat protein 1,CAGH1,CAGH1A,CAS-interacting zinc finger protein,CIZ,Ciz,ERDA2,NMP4,NP,Nmp4,Nuclear matrix transcription factor 4 (Nuclear matrix protein 4),TNRC1,Trinucleotide repeat-containing gene 1 protein,ZNF384,Zfp384,Zinc finger protein 384,Znf384
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP6194-Ag-1/ GM-Tg-hg-IP6194-Ag-2 | Human ZNF384 protein | Human |
| GM-Tg-rg-IP6194-Ag-1/ GM-Tg-rg-IP6194-Ag-2 | Rat ZNF384 protein | Rat |
| GM-Tg-mg-IP6194-Ag-1/ GM-Tg-mg-IP6194-Ag-2 | Mouse ZNF384 protein | Mouse |
| GM-Tg-cynog-IP6194-Ag-1/ GM-Tg-cynog-IP6194-Ag-2 | Cynomolgus/Rhesus macaque ZNF384 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP6194-Ag-1/ GM-Tg-felg-IP6194-Ag-2 | Feline ZNF384 protein | Feline |
| GM-Tg-cang-IP6194-Ag-1/ GM-Tg-cang-IP6194-Ag-2 | Canine ZNF384 protein | Canine |
| GM-Tg-bovg-IP6194-Ag-1/ GM-Tg-bovg-IP6194-Ag-2 | Bovine ZNF384 protein | Bovine |
| GM-Tg-equg-IP6194-Ag-1/ GM-Tg-equg-IP6194-Ag-2 | Equine ZNF384 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP6194-Ag-1/ GM-Tg-hg-IP6194-Ag-2;
GM-Tg-rg-IP6194-Ag-1/ GM-Tg-rg-IP6194-Ag-2;
GM-Tg-mg-IP6194-Ag-1/ GM-Tg-mg-IP6194-Ag-2; GM-Tg-cynog-IP6194-Ag-1/ GM-Tg-cynog-IP6194-Ag-2; GM-Tg-felg-IP6194-Ag-1/ GM-Tg-felg-IP6194-Ag-2; GM-Tg-cang-IP6194-Ag-1/ GM-Tg-cang-IP6194-Ag-2; GM-Tg-bovg-IP6194-Ag-1/ GM-Tg-bovg-IP6194-Ag-2; GM-Tg-equg-IP6194-Ag-1/ GM-Tg-equg-IP6194-Ag-2 |
| Products Name | ZNF384 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ZNF384 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ZNF384 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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GMab, developed by GeneMedi, constitutes an
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monoclonal antibodies, each meticulously
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.