Recombinant multi-species CHOP; GADD153/CHOP/DDIT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHOP; GADD153/CHOP/DDIT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
The Alternative Names of target: AltDDIT3,C/EBPzeta,CEBPZ,CHOP,CHOP-10,CHOP10,Chop10,DDIT3,Ddit3,GADD153,Gadd153,RM4,chop,gadd153

Target products collectionGo to CHOP; GADD153/CHOP/DDIT3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6112-Ag-1/ GM-Tg-hg-IP6112-Ag-2 Human CHOP; GADD153/CHOP/DDIT3 protein Human
GM-Tg-rg-IP6112-Ag-1/ GM-Tg-rg-IP6112-Ag-2 Rat CHOP; GADD153/CHOP/DDIT3 protein Rat
GM-Tg-mg-IP6112-Ag-1/ GM-Tg-mg-IP6112-Ag-2 Mouse CHOP; GADD153/CHOP/DDIT3 protein Mouse
GM-Tg-cynog-IP6112-Ag-1/ GM-Tg-cynog-IP6112-Ag-2 Cynomolgus/Rhesus macaque CHOP; GADD153/CHOP/DDIT3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6112-Ag-1/ GM-Tg-felg-IP6112-Ag-2 Feline CHOP; GADD153/CHOP/DDIT3 protein Feline
GM-Tg-cang-IP6112-Ag-1/ GM-Tg-cang-IP6112-Ag-2 Canine CHOP; GADD153/CHOP/DDIT3 protein Canine
GM-Tg-bovg-IP6112-Ag-1/ GM-Tg-bovg-IP6112-Ag-2 Bovine CHOP; GADD153/CHOP/DDIT3 protein Bovine
GM-Tg-equg-IP6112-Ag-1/ GM-Tg-equg-IP6112-Ag-2 Equine CHOP; GADD153/CHOP/DDIT3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6112-Ag-1/ GM-Tg-hg-IP6112-Ag-2; GM-Tg-rg-IP6112-Ag-1/ GM-Tg-rg-IP6112-Ag-2;
GM-Tg-mg-IP6112-Ag-1/ GM-Tg-mg-IP6112-Ag-2; GM-Tg-cynog-IP6112-Ag-1/ GM-Tg-cynog-IP6112-Ag-2;
GM-Tg-felg-IP6112-Ag-1/ GM-Tg-felg-IP6112-Ag-2; GM-Tg-cang-IP6112-Ag-1/ GM-Tg-cang-IP6112-Ag-2;
GM-Tg-bovg-IP6112-Ag-1/ GM-Tg-bovg-IP6112-Ag-2; GM-Tg-equg-IP6112-Ag-1/ GM-Tg-equg-IP6112-Ag-2
Products Name CHOP; GADD153/CHOP/DDIT3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CHOP; GADD153/CHOP/DDIT3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHOP; GADD153/CHOP/DDIT3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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