Recombinant multi-species APOBEC3H protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine APOBEC3H protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
The Alternative Names of target: A3H,APOBEC-related protein 10 (ARP-10),APOBEC3H,APOBEC3Z3,ARP-10,ARP10,Apobec,Apobec3,Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H (A3H),Arp3,Cem15,DNA dC->dU-editing enzyme APOBEC-3H,Gm20117,Rfv3

Target products collectionGo to APOBEC3H products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6108-Ag-1/ GM-Tg-hg-IP6108-Ag-2 Human APOBEC3H protein Human
GM-Tg-rg-IP6108-Ag-1/ GM-Tg-rg-IP6108-Ag-2 Rat APOBEC3H protein Rat
GM-Tg-mg-IP6108-Ag-1/ GM-Tg-mg-IP6108-Ag-2 Mouse APOBEC3H protein Mouse
GM-Tg-cynog-IP6108-Ag-1/ GM-Tg-cynog-IP6108-Ag-2 Cynomolgus/Rhesus macaque APOBEC3H protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6108-Ag-1/ GM-Tg-felg-IP6108-Ag-2 Feline APOBEC3H protein Feline
GM-Tg-cang-IP6108-Ag-1/ GM-Tg-cang-IP6108-Ag-2 Canine APOBEC3H protein Canine
GM-Tg-bovg-IP6108-Ag-1/ GM-Tg-bovg-IP6108-Ag-2 Bovine APOBEC3H protein Bovine
GM-Tg-equg-IP6108-Ag-1/ GM-Tg-equg-IP6108-Ag-2 Equine APOBEC3H protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6108-Ag-1/ GM-Tg-hg-IP6108-Ag-2; GM-Tg-rg-IP6108-Ag-1/ GM-Tg-rg-IP6108-Ag-2;
GM-Tg-mg-IP6108-Ag-1/ GM-Tg-mg-IP6108-Ag-2; GM-Tg-cynog-IP6108-Ag-1/ GM-Tg-cynog-IP6108-Ag-2;
GM-Tg-felg-IP6108-Ag-1/ GM-Tg-felg-IP6108-Ag-2; GM-Tg-cang-IP6108-Ag-1/ GM-Tg-cang-IP6108-Ag-2;
GM-Tg-bovg-IP6108-Ag-1/ GM-Tg-bovg-IP6108-Ag-2; GM-Tg-equg-IP6108-Ag-1/ GM-Tg-equg-IP6108-Ag-2
Products Name APOBEC3H protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name APOBEC3H
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine APOBEC3H protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.