Recombinant multi-species DCX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DCX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
The Alternative Names of target: DBCN,DC,DCX,Dbct,Dcx,Doublin,LISX,Lissencephalin-X (Lis-X),Neuronal migration protein doublecortin,SCLH,XLIS

Target products collectionGo to DCX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6099-Ag-1/ GM-Tg-hg-IP6099-Ag-2 Human DCX protein Human
GM-Tg-rg-IP6099-Ag-1/ GM-Tg-rg-IP6099-Ag-2 Rat DCX protein Rat
GM-Tg-mg-IP6099-Ag-1/ GM-Tg-mg-IP6099-Ag-2 Mouse DCX protein Mouse
GM-Tg-cynog-IP6099-Ag-1/ GM-Tg-cynog-IP6099-Ag-2 Cynomolgus/Rhesus macaque DCX protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6099-Ag-1/ GM-Tg-felg-IP6099-Ag-2 Feline DCX protein Feline
GM-Tg-cang-IP6099-Ag-1/ GM-Tg-cang-IP6099-Ag-2 Canine DCX protein Canine
GM-Tg-bovg-IP6099-Ag-1/ GM-Tg-bovg-IP6099-Ag-2 Bovine DCX protein Bovine
GM-Tg-equg-IP6099-Ag-1/ GM-Tg-equg-IP6099-Ag-2 Equine DCX protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6099-Ag-1/ GM-Tg-hg-IP6099-Ag-2; GM-Tg-rg-IP6099-Ag-1/ GM-Tg-rg-IP6099-Ag-2;
GM-Tg-mg-IP6099-Ag-1/ GM-Tg-mg-IP6099-Ag-2; GM-Tg-cynog-IP6099-Ag-1/ GM-Tg-cynog-IP6099-Ag-2;
GM-Tg-felg-IP6099-Ag-1/ GM-Tg-felg-IP6099-Ag-2; GM-Tg-cang-IP6099-Ag-1/ GM-Tg-cang-IP6099-Ag-2;
GM-Tg-bovg-IP6099-Ag-1/ GM-Tg-bovg-IP6099-Ag-2; GM-Tg-equg-IP6099-Ag-1/ GM-Tg-equg-IP6099-Ag-2
Products Name DCX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DCX
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DCX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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