Recombinant multi-species DAZL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DAZL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
The Alternative Names of target: DAZ homolog,DAZ-like autosomal,DAZH,DAZL,DAZL1,DAZLA,Daz-like,Dazh,Dazl,Dazl1,Dazla,Deleted in azoospermia-like,Deleted in azoospermia-like 1,SPGY-like-autosomal,SPGYLA,Tpx-2,Tpx2

Target products collectionGo to DAZL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6044-Ag-1/ GM-Tg-hg-IP6044-Ag-2 Human DAZL protein Human
GM-Tg-rg-IP6044-Ag-1/ GM-Tg-rg-IP6044-Ag-2 Rat DAZL protein Rat
GM-Tg-mg-IP6044-Ag-1/ GM-Tg-mg-IP6044-Ag-2 Mouse DAZL protein Mouse
GM-Tg-cynog-IP6044-Ag-1/ GM-Tg-cynog-IP6044-Ag-2 Cynomolgus/Rhesus macaque DAZL protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6044-Ag-1/ GM-Tg-felg-IP6044-Ag-2 Feline DAZL protein Feline
GM-Tg-cang-IP6044-Ag-1/ GM-Tg-cang-IP6044-Ag-2 Canine DAZL protein Canine
GM-Tg-bovg-IP6044-Ag-1/ GM-Tg-bovg-IP6044-Ag-2 Bovine DAZL protein Bovine
GM-Tg-equg-IP6044-Ag-1/ GM-Tg-equg-IP6044-Ag-2 Equine DAZL protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6044-Ag-1/ GM-Tg-hg-IP6044-Ag-2; GM-Tg-rg-IP6044-Ag-1/ GM-Tg-rg-IP6044-Ag-2;
GM-Tg-mg-IP6044-Ag-1/ GM-Tg-mg-IP6044-Ag-2; GM-Tg-cynog-IP6044-Ag-1/ GM-Tg-cynog-IP6044-Ag-2;
GM-Tg-felg-IP6044-Ag-1/ GM-Tg-felg-IP6044-Ag-2; GM-Tg-cang-IP6044-Ag-1/ GM-Tg-cang-IP6044-Ag-2;
GM-Tg-bovg-IP6044-Ag-1/ GM-Tg-bovg-IP6044-Ag-2; GM-Tg-equg-IP6044-Ag-1/ GM-Tg-equg-IP6044-Ag-2
Products Name DAZL protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DAZL
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DAZL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.