Recombinant multi-species DAZ1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DAZ1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains. [provided by RefSeq, Jul 2008]
The Alternative Names of target: DAZ,DAZ1,Deleted in azoospermia protein 1,SPGY
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP6040-Ag-1/ GM-Tg-hg-IP6040-Ag-2 | Human DAZ1 protein | Human |
| GM-Tg-rg-IP6040-Ag-1/ GM-Tg-rg-IP6040-Ag-2 | Rat DAZ1 protein | Rat |
| GM-Tg-mg-IP6040-Ag-1/ GM-Tg-mg-IP6040-Ag-2 | Mouse DAZ1 protein | Mouse |
| GM-Tg-cynog-IP6040-Ag-1/ GM-Tg-cynog-IP6040-Ag-2 | Cynomolgus/Rhesus macaque DAZ1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP6040-Ag-1/ GM-Tg-felg-IP6040-Ag-2 | Feline DAZ1 protein | Feline |
| GM-Tg-cang-IP6040-Ag-1/ GM-Tg-cang-IP6040-Ag-2 | Canine DAZ1 protein | Canine |
| GM-Tg-bovg-IP6040-Ag-1/ GM-Tg-bovg-IP6040-Ag-2 | Bovine DAZ1 protein | Bovine |
| GM-Tg-equg-IP6040-Ag-1/ GM-Tg-equg-IP6040-Ag-2 | Equine DAZ1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP6040-Ag-1/ GM-Tg-hg-IP6040-Ag-2;
GM-Tg-rg-IP6040-Ag-1/ GM-Tg-rg-IP6040-Ag-2;
GM-Tg-mg-IP6040-Ag-1/ GM-Tg-mg-IP6040-Ag-2; GM-Tg-cynog-IP6040-Ag-1/ GM-Tg-cynog-IP6040-Ag-2; GM-Tg-felg-IP6040-Ag-1/ GM-Tg-felg-IP6040-Ag-2; GM-Tg-cang-IP6040-Ag-1/ GM-Tg-cang-IP6040-Ag-2; GM-Tg-bovg-IP6040-Ag-1/ GM-Tg-bovg-IP6040-Ag-2; GM-Tg-equg-IP6040-Ag-1/ GM-Tg-equg-IP6040-Ag-2 |
| Products Name | DAZ1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DAZ1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DAZ1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
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pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.