Recombinant multi-species DGKB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DGKB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
The Alternative Names of target: 6430574F24,90 kDa diacylglycerol kinase,90kda,C630029D13Rik,DAG kinase beta,DAGK2,DGK,DGK-BETA,DGK-beta,DGKB,Dagk,Dgkb,Diacylglycerol kinase beta,Diglyceride kinase beta (DGK-beta),mKIAA0718

Target products collectionGo to DGKB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP6023-Ag-1/ GM-Tg-hg-IP6023-Ag-2 Human DGKB protein Human
GM-Tg-rg-IP6023-Ag-1/ GM-Tg-rg-IP6023-Ag-2 Rat DGKB protein Rat
GM-Tg-mg-IP6023-Ag-1/ GM-Tg-mg-IP6023-Ag-2 Mouse DGKB protein Mouse
GM-Tg-cynog-IP6023-Ag-1/ GM-Tg-cynog-IP6023-Ag-2 Cynomolgus/Rhesus macaque DGKB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP6023-Ag-1/ GM-Tg-felg-IP6023-Ag-2 Feline DGKB protein Feline
GM-Tg-cang-IP6023-Ag-1/ GM-Tg-cang-IP6023-Ag-2 Canine DGKB protein Canine
GM-Tg-bovg-IP6023-Ag-1/ GM-Tg-bovg-IP6023-Ag-2 Bovine DGKB protein Bovine
GM-Tg-equg-IP6023-Ag-1/ GM-Tg-equg-IP6023-Ag-2 Equine DGKB protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP6023-Ag-1/ GM-Tg-hg-IP6023-Ag-2; GM-Tg-rg-IP6023-Ag-1/ GM-Tg-rg-IP6023-Ag-2;
GM-Tg-mg-IP6023-Ag-1/ GM-Tg-mg-IP6023-Ag-2; GM-Tg-cynog-IP6023-Ag-1/ GM-Tg-cynog-IP6023-Ag-2;
GM-Tg-felg-IP6023-Ag-1/ GM-Tg-felg-IP6023-Ag-2; GM-Tg-cang-IP6023-Ag-1/ GM-Tg-cang-IP6023-Ag-2;
GM-Tg-bovg-IP6023-Ag-1/ GM-Tg-bovg-IP6023-Ag-2; GM-Tg-equg-IP6023-Ag-1/ GM-Tg-equg-IP6023-Ag-2
Products Name DGKB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DGKB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DGKB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.