Recombinant multi-species DGKA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DGKA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2017]
The Alternative Names of target: 80 kDa diacylglycerol kinase,80kDa,DAG kinase alpha,DAGK,DAGK1,DGK-alpha,DGKA,Dagk1,Dgka,Diacylglycerol kinase alpha,Diglyceride kinase alpha (DGK-alpha)
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP6021-Ag-1/ GM-Tg-hg-IP6021-Ag-2 | Human DGKA protein | Human |
| GM-Tg-rg-IP6021-Ag-1/ GM-Tg-rg-IP6021-Ag-2 | Rat DGKA protein | Rat |
| GM-Tg-mg-IP6021-Ag-1/ GM-Tg-mg-IP6021-Ag-2 | Mouse DGKA protein | Mouse |
| GM-Tg-cynog-IP6021-Ag-1/ GM-Tg-cynog-IP6021-Ag-2 | Cynomolgus/Rhesus macaque DGKA protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP6021-Ag-1/ GM-Tg-felg-IP6021-Ag-2 | Feline DGKA protein | Feline |
| GM-Tg-cang-IP6021-Ag-1/ GM-Tg-cang-IP6021-Ag-2 | Canine DGKA protein | Canine |
| GM-Tg-bovg-IP6021-Ag-1/ GM-Tg-bovg-IP6021-Ag-2 | Bovine DGKA protein | Bovine |
| GM-Tg-equg-IP6021-Ag-1/ GM-Tg-equg-IP6021-Ag-2 | Equine DGKA protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP6021-Ag-1/ GM-Tg-hg-IP6021-Ag-2;
GM-Tg-rg-IP6021-Ag-1/ GM-Tg-rg-IP6021-Ag-2;
GM-Tg-mg-IP6021-Ag-1/ GM-Tg-mg-IP6021-Ag-2; GM-Tg-cynog-IP6021-Ag-1/ GM-Tg-cynog-IP6021-Ag-2; GM-Tg-felg-IP6021-Ag-1/ GM-Tg-felg-IP6021-Ag-2; GM-Tg-cang-IP6021-Ag-1/ GM-Tg-cang-IP6021-Ag-2; GM-Tg-bovg-IP6021-Ag-1/ GM-Tg-bovg-IP6021-Ag-2; GM-Tg-equg-IP6021-Ag-1/ GM-Tg-equg-IP6021-Ag-2 |
| Products Name | DGKA protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DGKA |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DGKA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.