Recombinant multi-species NKX2-5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NKX2-5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
The Alternative Names of target: CHNG5,CSX,CSX1,Cardiac-specific homeobox,Csx,HLHS2,Homeobox protein CSX,Homeobox protein NK-2 homolog E,Homeobox protein Nkx-2.5,NKX2-5,NKX2.5,NKX2E,NKX4-1,Nkx-2.5,Nkx2-5,Nkx2.5,VSD3,tinman

Target products collectionGo to NKX2-5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP5812-Ag-1/ GM-Tg-hg-IP5812-Ag-2 Human NKX2-5 protein Human
GM-Tg-rg-IP5812-Ag-1/ GM-Tg-rg-IP5812-Ag-2 Rat NKX2-5 protein Rat
GM-Tg-mg-IP5812-Ag-1/ GM-Tg-mg-IP5812-Ag-2 Mouse NKX2-5 protein Mouse
GM-Tg-cynog-IP5812-Ag-1/ GM-Tg-cynog-IP5812-Ag-2 Cynomolgus/Rhesus macaque NKX2-5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP5812-Ag-1/ GM-Tg-felg-IP5812-Ag-2 Feline NKX2-5 protein Feline
GM-Tg-cang-IP5812-Ag-1/ GM-Tg-cang-IP5812-Ag-2 Canine NKX2-5 protein Canine
GM-Tg-bovg-IP5812-Ag-1/ GM-Tg-bovg-IP5812-Ag-2 Bovine NKX2-5 protein Bovine
GM-Tg-equg-IP5812-Ag-1/ GM-Tg-equg-IP5812-Ag-2 Equine NKX2-5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP5812-Ag-1/ GM-Tg-hg-IP5812-Ag-2; GM-Tg-rg-IP5812-Ag-1/ GM-Tg-rg-IP5812-Ag-2;
GM-Tg-mg-IP5812-Ag-1/ GM-Tg-mg-IP5812-Ag-2; GM-Tg-cynog-IP5812-Ag-1/ GM-Tg-cynog-IP5812-Ag-2;
GM-Tg-felg-IP5812-Ag-1/ GM-Tg-felg-IP5812-Ag-2; GM-Tg-cang-IP5812-Ag-1/ GM-Tg-cang-IP5812-Ag-2;
GM-Tg-bovg-IP5812-Ag-1/ GM-Tg-bovg-IP5812-Ag-2; GM-Tg-equg-IP5812-Ag-1/ GM-Tg-equg-IP5812-Ag-2
Products Name NKX2-5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NKX2-5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NKX2-5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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