Recombinant multi-species TOM1L2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TOM1L2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Apr 2017]
The Alternative Names of target: 2900016I08Rik,A730055F12Rik,Srebf1,TOM1-like protein 2,TOM1L2,Target of Myb-like protein 2,Tom1l2

Target products collectionGo to TOM1L2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP5755-Ag-1/ GM-Tg-hg-IP5755-Ag-2 Human TOM1L2 protein Human
GM-Tg-rg-IP5755-Ag-1/ GM-Tg-rg-IP5755-Ag-2 Rat TOM1L2 protein Rat
GM-Tg-mg-IP5755-Ag-1/ GM-Tg-mg-IP5755-Ag-2 Mouse TOM1L2 protein Mouse
GM-Tg-cynog-IP5755-Ag-1/ GM-Tg-cynog-IP5755-Ag-2 Cynomolgus/Rhesus macaque TOM1L2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP5755-Ag-1/ GM-Tg-felg-IP5755-Ag-2 Feline TOM1L2 protein Feline
GM-Tg-cang-IP5755-Ag-1/ GM-Tg-cang-IP5755-Ag-2 Canine TOM1L2 protein Canine
GM-Tg-bovg-IP5755-Ag-1/ GM-Tg-bovg-IP5755-Ag-2 Bovine TOM1L2 protein Bovine
GM-Tg-equg-IP5755-Ag-1/ GM-Tg-equg-IP5755-Ag-2 Equine TOM1L2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP5755-Ag-1/ GM-Tg-hg-IP5755-Ag-2; GM-Tg-rg-IP5755-Ag-1/ GM-Tg-rg-IP5755-Ag-2;
GM-Tg-mg-IP5755-Ag-1/ GM-Tg-mg-IP5755-Ag-2; GM-Tg-cynog-IP5755-Ag-1/ GM-Tg-cynog-IP5755-Ag-2;
GM-Tg-felg-IP5755-Ag-1/ GM-Tg-felg-IP5755-Ag-2; GM-Tg-cang-IP5755-Ag-1/ GM-Tg-cang-IP5755-Ag-2;
GM-Tg-bovg-IP5755-Ag-1/ GM-Tg-bovg-IP5755-Ag-2; GM-Tg-equg-IP5755-Ag-1/ GM-Tg-equg-IP5755-Ag-2
Products Name TOM1L2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TOM1L2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TOM1L2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.