Recombinant multi-species CRX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CORD2,CRD,CRX,Cone-rod homeobox protein,Crx,Crx1,LCA7,OTX3

Target products collectionGo to CRX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP5635-Ag-1/ GM-Tg-hg-IP5635-Ag-2 Human CRX protein Human
GM-Tg-rg-IP5635-Ag-1/ GM-Tg-rg-IP5635-Ag-2 Rat CRX protein Rat
GM-Tg-mg-IP5635-Ag-1/ GM-Tg-mg-IP5635-Ag-2 Mouse CRX protein Mouse
GM-Tg-cynog-IP5635-Ag-1/ GM-Tg-cynog-IP5635-Ag-2 Cynomolgus/Rhesus macaque CRX protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP5635-Ag-1/ GM-Tg-felg-IP5635-Ag-2 Feline CRX protein Feline
GM-Tg-cang-IP5635-Ag-1/ GM-Tg-cang-IP5635-Ag-2 Canine CRX protein Canine
GM-Tg-bovg-IP5635-Ag-1/ GM-Tg-bovg-IP5635-Ag-2 Bovine CRX protein Bovine
GM-Tg-equg-IP5635-Ag-1/ GM-Tg-equg-IP5635-Ag-2 Equine CRX protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP5635-Ag-1/ GM-Tg-hg-IP5635-Ag-2; GM-Tg-rg-IP5635-Ag-1/ GM-Tg-rg-IP5635-Ag-2;
GM-Tg-mg-IP5635-Ag-1/ GM-Tg-mg-IP5635-Ag-2; GM-Tg-cynog-IP5635-Ag-1/ GM-Tg-cynog-IP5635-Ag-2;
GM-Tg-felg-IP5635-Ag-1/ GM-Tg-felg-IP5635-Ag-2; GM-Tg-cang-IP5635-Ag-1/ GM-Tg-cang-IP5635-Ag-2;
GM-Tg-bovg-IP5635-Ag-1/ GM-Tg-bovg-IP5635-Ag-2; GM-Tg-equg-IP5635-Ag-1/ GM-Tg-equg-IP5635-Ag-2
Products Name CRX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CRX
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.