Recombinant multi-species POLGARF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLGARF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene uses the same transcript as the POLG gene but has a CUG start codon and an alternate reading frame that makes a 260 aa protein. This protein is distinct from POLG isoforms and may interact with P32 (also known as C1QBP), a mitochondrial matrix protein thought to be involved in the expression of mitochondrial genome-encoded proteins. POLGARF protein may bind P32 and sequester it in the nucleolus. Interestingly, some disease-causing mutations thought to be in POLG may instead be associated with POLGARF. [provided by RefSeq, May 2022]
The Alternative Names of target: ORF-Y,POLG,POLG alternative reading frame,POLGARF

Target products collectionGo to POLGARF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP5176-Ag-1/ GM-Tg-hg-IP5176-Ag-2 Human POLGARF protein Human
GM-Tg-rg-IP5176-Ag-1/ GM-Tg-rg-IP5176-Ag-2 Rat POLGARF protein Rat
GM-Tg-mg-IP5176-Ag-1/ GM-Tg-mg-IP5176-Ag-2 Mouse POLGARF protein Mouse
GM-Tg-cynog-IP5176-Ag-1/ GM-Tg-cynog-IP5176-Ag-2 Cynomolgus/Rhesus macaque POLGARF protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP5176-Ag-1/ GM-Tg-felg-IP5176-Ag-2 Feline POLGARF protein Feline
GM-Tg-cang-IP5176-Ag-1/ GM-Tg-cang-IP5176-Ag-2 Canine POLGARF protein Canine
GM-Tg-bovg-IP5176-Ag-1/ GM-Tg-bovg-IP5176-Ag-2 Bovine POLGARF protein Bovine
GM-Tg-equg-IP5176-Ag-1/ GM-Tg-equg-IP5176-Ag-2 Equine POLGARF protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP5176-Ag-1/ GM-Tg-hg-IP5176-Ag-2; GM-Tg-rg-IP5176-Ag-1/ GM-Tg-rg-IP5176-Ag-2;
GM-Tg-mg-IP5176-Ag-1/ GM-Tg-mg-IP5176-Ag-2; GM-Tg-cynog-IP5176-Ag-1/ GM-Tg-cynog-IP5176-Ag-2;
GM-Tg-felg-IP5176-Ag-1/ GM-Tg-felg-IP5176-Ag-2; GM-Tg-cang-IP5176-Ag-1/ GM-Tg-cang-IP5176-Ag-2;
GM-Tg-bovg-IP5176-Ag-1/ GM-Tg-bovg-IP5176-Ag-2; GM-Tg-equg-IP5176-Ag-1/ GM-Tg-equg-IP5176-Ag-2
Products Name POLGARF protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name POLGARF
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLGARF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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